{"id":"W4385442820","doi":"10.1002/cam4.6191","title":"Blood and saliva‐derived <scp>ctDNA</scp> is a marker of residual disease after treatment and correlates with recurrence in human papillomavirus‐associated head and neck cancer","year":2023,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"McGill University Health Centre","keywords":"Saliva; Concordance; Medicine; Liquid biopsy; Biomarker; Head and neck cancer; Internal medicine; Oncology; Biopsy; Cancer; Pathological; Gastroenterology; Human papillomavirus; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008045472,0.0001865978,0.0002764323,0.00006225324,0.00004626129,0.00000953168,0.0000422272,0.00008016735,0.00002058027],"category_scores_gemma":[0.0001153494,0.0001445681,0.00001645081,0.0001375879,0.0002865166,0.00000448194,0.00006874211,0.00006152825,1.742231e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003476913,"about_ca_system_score_gemma":0.0001463684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001470399,"about_ca_topic_score_gemma":0.003379562,"domain_scores_codex":[0.999078,0.00002877619,0.0001972183,0.0003796536,0.00009283807,0.0002235676],"domain_scores_gemma":[0.9994238,0.00006452882,0.00009595888,0.0001648591,0.0000562911,0.0001945661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002409665,0.00006518604,0.9391602,0.0001008985,0.0001684849,0.00004345995,0.001142465,0.00001048409,0.05495596,0.000007801049,0.002298206,0.001805924],"study_design_scores_gemma":[0.005057366,0.001140111,0.9790175,0.0007463054,0.0002836639,0.000003545598,0.0002482207,0.00003865916,0.01032062,0.00008467204,0.002932491,0.0001268232],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9565555,0.04220716,6.884524e-7,0.0005582069,0.00006330053,0.0002424719,0.0003149865,0.000006982317,0.00005070783],"genre_scores_gemma":[0.9470712,0.05181249,0.000009822421,0.0003700595,0.0001147827,0.0001631079,0.00008877204,0.00002097065,0.0003488124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04463534,"threshold_uncertainty_score":0.5895315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01241596039003079,"score_gpt":0.2753336024432281,"score_spread":0.2629176420531973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}