{"id":"W4385446815","doi":"10.1002/art.42665","title":"Liposomal <scp>AntagomiR</scp>‐155‐5p Restores <scp>Anti‐Inflammatory</scp> Macrophages and Improves Arthritis in Preclinical Models of Rheumatoid Arthritis","year":2023,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Foundation for Research in Rheumatology; Versus Arthritis; University of Glasgow","keywords":"Arthritis; Medicine; Rheumatoid arthritis; Liposome; Pharmacology; Cationic liposome; Immunology; Cancer research; Chemistry; Transfection; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001728515,0.0005241013,0.0004501145,0.0003384999,0.0001444976,0.0002733271,0.0002219873,0.0004404238,0.001227534],"category_scores_gemma":[0.0001028085,0.0001810172,0.0002653909,0.0001310625,0.0003654527,0.0002759326,0.0001316189,0.0007523165,0.0005214002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003147334,"about_ca_system_score_gemma":0.0002717589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006396607,"about_ca_topic_score_gemma":0.0008407371,"domain_scores_codex":[0.9998305,0.00002226982,0.00002374044,0.00003163725,0.00004796726,0.00004389709],"domain_scores_gemma":[0.9998828,0.00001216116,0.00004775246,0.00001012755,0.00001526556,0.00003177812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002829994,0.00007437509,0.00004724877,0.00005248945,0.000006733403,0.00002384354,0.000007418549,0.00005757833,0.9984584,0.00003835079,0.00003945837,0.0009110115],"study_design_scores_gemma":[0.00007369365,0.001308043,0.00110649,0.00000807183,0.00002752048,0.0001347899,0.0000183918,0.0004765656,0.9954354,0.0000211419,0.001385029,0.000004845203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993659,0.001442934,0.002659868,0.0001722179,0.00008012282,0.00007390261,0.0003756474,0.0002362091,0.001300233],"genre_scores_gemma":[0.9942691,0.000756419,0.00204244,0.0000978521,0.00002287414,0.00007168269,0.0004105874,0.00003168529,0.002297332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001227534,"threshold_uncertainty_score":0.004106462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0133904246802296,"score_gpt":0.2505116045431066,"score_spread":0.237121179862877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}