{"id":"W4385487110","doi":"10.1186/s40168-023-01590-2","title":"Oligofructose improves small intestinal lipid-sensing mechanisms via alterations to the small intestinal microbiota","year":2023,"lang":"en","type":"article","venue":"Microbiome","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Environmental Health Sciences; National Institute of Food and Agriculture; National Institutes of Health; Arizona Department of Health Services; National Institute of Diabetes and Digestive and Kidney Diseases; Arizona Biomedical Research Commission; U.S. Department of Agriculture","keywords":"Biology; Gut flora; Bifidobacterium; Small intestine; Energy homeostasis; Prebiotic; Small intestinal bacterial overgrowth; Lipid metabolism; Internal medicine; Endocrinology; Food science; Immunology; Lactobacillus; Medicine; Irritable bowel syndrome; Obesity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004448332,0.0003855052,0.000263686,0.0002356247,0.0004808082,0.0001612619,0.0005681411,0.0001946341,0.00002506049],"category_scores_gemma":[0.0001217613,0.0003228607,0.0001694387,0.0006700453,0.0001214272,0.000005586463,0.0005831051,0.0002714033,0.000660015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006097801,"about_ca_system_score_gemma":0.0001954944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000213611,"about_ca_topic_score_gemma":0.0009517399,"domain_scores_codex":[0.9977691,0.0001182506,0.0004692061,0.0007509523,0.00007029289,0.000822243],"domain_scores_gemma":[0.9986799,0.00004101997,0.0001346661,0.0007258304,0.0002038717,0.0002146958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004431331,0.00004489521,0.00003029331,0.00004723787,0.00003635722,0.00001156772,0.0002440902,0.00002482162,0.9844211,0.00006663585,0.01042923,0.004599494],"study_design_scores_gemma":[0.0005186351,0.0004963812,0.002060396,0.0001085494,0.00004377922,0.0007859883,0.0001777071,0.0001863435,0.9194535,0.0001183794,0.07548857,0.0005617865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9511368,0.0001333811,0.04248254,0.004121161,0.0009568797,0.0007719744,0.0001154943,0.0001497361,0.0001319745],"genre_scores_gemma":[0.9285477,0.0000582817,0.05608028,0.00713474,0.001272665,0.00004365066,0.001387681,0.0001634134,0.005311594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06505934,"threshold_uncertainty_score":0.9999223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01786160729902291,"score_gpt":0.2505272227804359,"score_spread":0.232665615481413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}