{"id":"W4385487110","doi":"10.1186/s40168-023-01590-2","title":"Oligofructose improves small intestinal lipid-sensing mechanisms via alterations to the small intestinal microbiota","year":2023,"lang":"en","type":"article","venue":"Microbiome","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Environmental Health Sciences; National Institute of Food and Agriculture; National Institutes of Health; Arizona Department of Health Services; National Institute of Diabetes and Digestive and Kidney Diseases; Arizona Biomedical Research Commission; U.S. Department of Agriculture","keywords":"Biology; Gut flora; Bifidobacterium; Small intestine; Energy homeostasis; Prebiotic; Small intestinal bacterial overgrowth; Lipid metabolism; Internal medicine; Endocrinology; Food science; Immunology; Lactobacillus; Medicine; Irritable bowel syndrome; Obesity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006287409,0.0004036879,0.0002824172,0.0002338208,0.000111806,0.0001911632,0.0002128977,0.0002931207,0.003343215],"category_scores_gemma":[0.00006755713,0.0000630639,0.0002996812,0.0001505943,0.0001505378,0.0001938394,0.0001745793,0.0003794041,0.0002305757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002610907,"about_ca_system_score_gemma":0.0002497625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001725755,"about_ca_topic_score_gemma":0.002816252,"domain_scores_codex":[0.999948,0.00000738276,0.000002690572,0.00001092676,0.0000117074,0.00001929144],"domain_scores_gemma":[0.999949,0.000004070011,0.00001651494,0.000003626622,0.000009321023,0.00001746049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002389191,0.0001516588,0.0004894426,0.0002838084,0.00002756355,0.00009503437,0.00001320318,0.00008148186,0.9825283,0.0001317296,0.0002786513,0.01353003],"study_design_scores_gemma":[0.0001996719,0.004309453,0.03844374,0.0001119124,0.0001639723,0.0003260022,0.0001211581,0.0009214227,0.9384129,0.0002554322,0.01671321,0.00002113473],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837896,0.007685588,0.002892534,0.0004573471,0.0001407278,0.0000768141,0.001563738,0.0001421819,0.003251364],"genre_scores_gemma":[0.9805481,0.006626436,0.004442161,0.0002614498,0.00004727532,0.00007951002,0.001365879,0.00003389184,0.00659526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003343215,"threshold_uncertainty_score":0.01118422,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01786160729902291,"score_gpt":0.2505272227804359,"score_spread":0.232665615481413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}