{"id":"W4385503298","doi":"10.1016/j.celrep.2023.112879","title":"Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma","year":2023,"lang":"en","type":"article","venue":"Cell Reports","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute on Minority Health and Health Disparities; National Institutes of Health; National Cancer Institute; Rally Foundation","keywords":"Neuroblastoma; Autoimmunity; Polyclonal antibodies; Immunology; Lymphoma; Biology; Pathology; Major histocompatibility complex; Medicine; Antigen; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001015219,0.00009580101,0.0001249836,0.0002647081,0.0001691739,0.0002077192,0.00006829399,0.0001051535,0.0007798419],"category_scores_gemma":[0.0002472762,0.00008580528,0.00007689249,0.0001537423,0.0001641366,0.000121934,0.0002402169,0.0001217043,0.0001143652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001383046,"about_ca_system_score_gemma":0.0001361973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009001636,"about_ca_topic_score_gemma":0.001524976,"domain_scores_codex":[0.9999386,0.00001244531,0.000004891561,0.00001779335,0.00001478334,0.00001154031],"domain_scores_gemma":[0.9998981,0.00001907199,0.00004196593,0.000007299857,0.00001159833,0.0000219697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003861097,0.0000425768,0.3849182,0.00008187427,0.00002903956,0.001360986,0.0005378048,0.0002029309,0.6049677,0.0002227359,0.0001444035,0.007105655],"study_design_scores_gemma":[0.00001318221,0.0002494607,0.971173,0.00002211465,0.00003258682,0.004847825,0.0006599055,0.000501775,0.02120828,0.0002727259,0.001012052,0.000006988764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999629,0.0001238444,0.00005241286,0.000005217633,7.480072e-7,0.000001051952,0.00003071186,0.000002577149,0.0001543673],"genre_scores_gemma":[0.9995694,0.0001432321,0.00008929584,0.000008729508,0.000002034837,0.000002535342,0.00006622847,0.000001444385,0.0001171073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009001636,"threshold_uncertainty_score":0.002608836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01575299172838856,"score_gpt":0.2752647688799102,"score_spread":0.2595117771515217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}