{"id":"W4385519816","doi":"10.1111/imcb.12676","title":"Uncoupling of Natural Killer cell functional maturation and cytolytic function in NOD mice","year":2023,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Université de Montréal; Canadian Institutes of Health Research; Cancer Research Society; Diabète Québec","keywords":"Cytotoxic T cell; Nod; Granzyme B; Biology; Granzyme; Cell biology; Immune system; Granzyme A; Immunology; Interleukin 21; NOD mice; Perforin; CD8; In vitro; In vivo; Autoimmunity; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002561107,0.0001945789,0.000305585,0.0004043441,0.0001623945,0.000007550703,0.00007279063,0.0005002681,0.0003508914],"category_scores_gemma":[0.0000374392,0.0001776517,0.00005410115,0.0002653543,0.0003212074,0.0001346853,0.0000952761,0.000512352,0.0003008158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002962163,"about_ca_system_score_gemma":0.00003279756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001096417,"about_ca_topic_score_gemma":0.00002613798,"domain_scores_codex":[0.9986917,0.000188291,0.000407328,0.0003687276,0.00001956095,0.0003243745],"domain_scores_gemma":[0.9993369,0.0002671383,0.0001759632,0.0001477182,0.00006050183,0.0000117632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001207588,0.00006783434,0.003738632,0.00003329521,0.00006405977,0.00000147914,0.0002110756,0.00001708616,0.9909222,0.0006237352,0.001104894,0.002008184],"study_design_scores_gemma":[0.009080516,0.001689965,0.2888546,0.00007698546,0.0001540099,0.0002012313,0.003552295,0.0008314085,0.6337665,0.001525649,0.0594763,0.0007904984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820953,0.008515464,0.000132614,0.0002129515,0.007544011,0.0001693972,0.000002822208,0.00007955611,0.001247896],"genre_scores_gemma":[0.9908219,0.001022196,0.00001408446,0.0001325396,0.00003339518,0.00002122556,0.0004164307,0.00001310627,0.007525142],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3571556,"threshold_uncertainty_score":0.7244425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007901525213609945,"score_gpt":0.2092279449223278,"score_spread":0.2013264197087178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}