{"id":"W4385521249","doi":"10.1136/jnis-2023-snis.379","title":"LB-005 Hemera 1 carboxyhemoglobin oxygendelivery for revascularization in acute stroke: a prospective, randomized phase 1 clinical trial","year":2023,"lang":"en","type":"article","venue":"","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Thrombolysis; Stroke (engine); Randomized controlled trial; Middle cerebral artery; Clinical endpoint; Revascularization; Modified Rankin Scale; Anesthesia; Internal medicine; Surgery; Cardiology; Ischemia; Ischemic stroke; Myocardial infarction","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001698962,0.001559901,0.001876169,0.0003845812,0.0004280121,0.001317778,0.0008262309,0.001965244,0.00670541],"category_scores_gemma":[0.001032859,0.0005110092,0.001198003,0.0004376633,0.0009776396,0.0008752571,0.0003138982,0.002114132,0.00118121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005600191,"about_ca_system_score_gemma":0.001365967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007307401,"about_ca_topic_score_gemma":0.001978406,"domain_scores_codex":[0.9995064,0.0002543622,0.00002591724,0.00008106638,0.00004095769,0.00009123862],"domain_scores_gemma":[0.9995006,0.00009171126,0.0001399123,0.00003982929,0.00003381871,0.0001941505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9505062,0.01470046,0.0009055039,0.0007943059,0.0007261994,0.00007060375,0.00005223211,0.0003477276,0.006383164,0.0002226324,0.002477375,0.02281363],"study_design_scores_gemma":[0.9283289,0.06766394,0.001881312,0.00004154428,0.0002793609,0.00004793145,0.00001691557,0.0003744027,0.0004146793,0.0001681084,0.00076843,0.00001450156],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768999,0.006565206,0.001012442,0.001409208,0.0005145624,0.008092529,0.001992376,0.0002630906,0.003250792],"genre_scores_gemma":[0.9705591,0.004780154,0.002817552,0.003247055,0.000817125,0.01106785,0.002580424,0.00005415493,0.004076659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00670541,"threshold_uncertainty_score":0.02243179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04566639844634908,"score_gpt":0.3872051637619214,"score_spread":0.3415387653155723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}