{"id":"W4385543338","doi":"10.1016/j.ymthe.2023.07.011","title":"Darwin’s gemmules and extracellular vesicles: A striking resemblance","year":2023,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Henan Institute of Science and Technology","keywords":"Context (archaeology); Extracellular vesicles; Darwin (ADL); Biology; Computer science; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003792876,0.0006856765,0.0004713989,0.0001800614,0.0001642113,0.0001739476,0.0007817926,0.001199756,0.00004162356],"category_scores_gemma":[0.0001127142,0.0007223611,0.0003285847,0.0002120315,0.0002802449,0.00000712793,0.0003188222,0.0009855403,0.00006677743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003251063,"about_ca_system_score_gemma":0.0001371427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001529908,"about_ca_topic_score_gemma":0.000002634077,"domain_scores_codex":[0.9965209,0.000361609,0.0004688469,0.001309706,0.0005470595,0.0007918479],"domain_scores_gemma":[0.9978861,0.00004856939,0.0002563455,0.001548634,0.0001083472,0.0001520089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008113153,0.00003871245,0.00008352408,0.0001116852,0.0002924304,0.001961215,0.00004184453,0.00001757866,0.7041146,0.00002755433,0.2865427,0.006687019],"study_design_scores_gemma":[0.0008224255,0.0001998575,0.00009996691,0.00009707148,0.00004787101,0.00004473886,0.00002457795,0.00004259482,0.1894924,0.0005223281,0.8078198,0.0007863233],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.6511391,0.1940502,0.00655944,0.1425718,0.001153748,0.00227878,0.0004070338,0.0004794479,0.001360435],"genre_scores_gemma":[0.230816,0.02800373,0.004971959,0.6875944,0.01262859,0.0008185654,0.008339885,0.002411409,0.02441549],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5450225,"threshold_uncertainty_score":0.9995227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02054923404398452,"score_gpt":0.2629320344345577,"score_spread":0.2423828003905732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}