{"id":"W4385543338","doi":"10.1016/j.ymthe.2023.07.011","title":"Darwin’s gemmules and extracellular vesicles: A striking resemblance","year":2023,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Henan Institute of Science and Technology","keywords":"Context (archaeology); Extracellular vesicles; Darwin (ADL); Biology; Computer science; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002119435,0.0003948321,0.0008629317,0.0004474784,0.001351161,0.002486082,0.001230705,0.01792947,0.001581331],"category_scores_gemma":[0.009383441,0.0002528363,0.0006053362,0.0002460038,0.004025893,0.003397775,0.001633868,0.01615787,0.0007016413],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002104831,"about_ca_system_score_gemma":0.0008383892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008044089,"about_ca_topic_score_gemma":0.001112914,"domain_scores_codex":[0.9985122,0.0005082385,0.00009514692,0.0002704313,0.0004431828,0.0001708768],"domain_scores_gemma":[0.9965653,0.002635818,0.0001607716,0.0002094456,0.000184681,0.0002440061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0005370607,0.0001107881,0.001271147,0.000338942,0.0001326296,0.02577418,0.0007501892,0.0004379388,0.001864828,0.2633196,0.627015,0.07844772],"study_design_scores_gemma":[0.0001656533,0.0001237747,0.0007081101,0.0001370288,0.00002531546,0.01305663,0.000262161,0.000637095,0.0009383758,0.1208783,0.8630227,0.00004489265],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.005882831,0.03414804,0.002469276,0.8948275,0.04919611,0.00003923329,0.00003626777,0.00005615613,0.01334471],"genre_scores_gemma":[0.1216952,0.0259172,0.002173457,0.6963707,0.1274918,0.0001308498,0.00004596232,0.0000991296,0.02607562],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01792947,"threshold_uncertainty_score":0.01527172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02054923404398452,"score_gpt":0.2629320344345577,"score_spread":0.2423828003905732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}