{"id":"W4385552853","doi":"10.51731/cjht.2023.706","title":"Ciltacabtagene Autoleucel (Carvykti)","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Reimbursement; Medicine; Drug; Refractory (planetary science); Antibody therapy; Intensive care medicine; Pharmacology; Antibody; Immunology; Health care; Monoclonal antibody; Political science","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001271951,0.0001262946,0.0004597237,0.001721786,0.0002090269,0.00003010469,0.0003564596,0.0001871214,0.0004651814],"category_scores_gemma":[0.0007881792,0.0001070612,0.0001294772,0.001236548,0.000241815,0.00006678007,0.00003278413,0.0007674705,0.0001149618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007153464,"about_ca_system_score_gemma":0.005581207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002686121,"about_ca_topic_score_gemma":0.001656535,"domain_scores_codex":[0.9981405,0.00005250514,0.0005289825,0.0001485473,0.0003449417,0.0007845046],"domain_scores_gemma":[0.9988563,0.00007371006,0.000204479,0.0003768966,0.000239604,0.0002489808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003265467,0.00001146483,0.005793798,0.0001407124,0.00007458132,0.001352934,0.0002537962,0.00001245322,0.003368208,0.0003301485,0.04686354,0.9417657],"study_design_scores_gemma":[0.00100992,0.0009587053,0.02622771,0.0002950287,0.00001474844,0.001145236,0.0032735,0.00007110045,0.004780557,0.002064853,0.9600157,0.0001430094],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.693117,0.05023756,0.0001198545,0.2497808,0.001040651,0.0007657135,0.00004008468,0.0008695309,0.004028871],"genre_scores_gemma":[0.9929139,0.002051619,0.0003597882,0.000716465,0.0000418706,0.000007052909,0.000005589965,0.00003394606,0.003869744],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9416227,"threshold_uncertainty_score":0.9900821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0766381167478992,"score_gpt":0.3608069469756653,"score_spread":0.2841688302277662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}