{"id":"W4385569071","doi":"10.1002/9781119983347.ch1","title":"Diabetes Mellitus and Natural Product‐based Drug Discovery","year":2023,"lang":"en","type":"other","venue":"","topic":"Natural Antidiabetic Agents Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Natural history; Diabetes mellitus; Type 2 Diabetes Mellitus; Insulin; Juvenile hormone; Medicine; Metformin; Natural product; Drug discovery; Endocrinology; Bioinformatics; Internal medicine; Biology; Hormone; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000836443,0.0003438373,0.0006185986,0.0002031653,0.00004408641,0.000028631,0.00007474756,0.000098324,0.0003348597],"category_scores_gemma":[0.0001449692,0.0002137842,0.0001000183,0.0001911126,0.0001980498,0.00004309697,0.0001175053,0.0003113548,0.0001798023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003349525,"about_ca_system_score_gemma":0.00004280951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001514587,"about_ca_topic_score_gemma":0.0002175443,"domain_scores_codex":[0.9986197,0.00002107023,0.0001746619,0.000522276,0.000307452,0.0003548401],"domain_scores_gemma":[0.9993889,0.00009110747,0.0000861769,0.0003234928,0.00003292738,0.00007742899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001390777,0.00004796898,0.01004539,0.0007598953,0.0003996351,0.00003056721,0.00002389588,2.523658e-8,0.0001837333,0.0000982309,0.9838238,0.004572894],"study_design_scores_gemma":[0.002261739,0.00011509,0.03505051,0.00266257,0.0008832453,0.000004606133,0.000129412,0.00005013261,0.006243187,0.00009892268,0.9514595,0.001041095],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.04634613,0.2748289,0.000009312407,0.02697612,0.007662258,0.005049075,0.0002395714,0.006476692,0.6324119],"genre_scores_gemma":[0.03720843,0.001534467,0.0004984206,0.0005724063,0.0006863648,0.00002758552,0.00005195957,0.0006182875,0.9588021],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.3263902,"threshold_uncertainty_score":0.8717865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00853519104657119,"score_gpt":0.2437566344739596,"score_spread":0.2352214434273884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}