{"id":"W4385578338","doi":"10.1093/noajnl/vdad070.004","title":"BSBM-07 HIGH-DIMENSIONAL HISTOPATHOLOGIC EVALUATION OF THE HYPOXIC MICROENVIRONMENT IN GLIOBLASTOMA","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; McMaster University Medical Centre; University of Toronto; Princess Margaret Cancer Centre","funders":"","keywords":"Hypoxia (environmental); Pathology; Biology; Angiogenesis; Immunohistochemistry; Cell type; Mass cytometry; Cell; Tumor microenvironment; Cancer research; Tumour heterogeneity; Phenotype; Medicine; Chemistry; Cancer; Tumor cells; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001905646,0.0001630494,0.0001782154,0.0008917667,0.0001680694,0.00024398,0.00009183192,0.0001834364,0.0008745706],"category_scores_gemma":[0.0001096154,0.000110689,0.0001072806,0.0003731697,0.000108739,0.0001151003,0.0001816298,0.000168945,0.0002165509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001586218,"about_ca_system_score_gemma":0.0001114238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001121214,"about_ca_topic_score_gemma":0.001238302,"domain_scores_codex":[0.9999248,0.0000126474,0.000005409207,0.000009576238,0.00003225665,0.00001535386],"domain_scores_gemma":[0.9999323,0.000007373596,0.00001385672,0.000004724433,0.00002128556,0.00002047289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002438775,0.0000297483,0.007986346,0.00004897387,0.00001362567,0.0001788372,0.00003929136,0.0001973467,0.9873289,0.00006195355,0.0001136623,0.003757343],"study_design_scores_gemma":[0.00001432678,0.0004882118,0.2910137,0.0000127788,0.00007764204,0.002626392,0.0002675399,0.007350454,0.6952306,0.0001338433,0.002762639,0.00002180287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916283,0.001020247,0.004943315,0.0000461339,0.00001502848,0.00004109406,0.000786442,0.0001200601,0.001399561],"genre_scores_gemma":[0.9893613,0.000604885,0.007939087,0.00003370285,0.000007517563,0.00005494553,0.0009919805,0.00002111033,0.0009853926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001121214,"threshold_uncertainty_score":0.002925754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01784740822459328,"score_gpt":0.3107935297692497,"score_spread":0.2929461215446564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}