{"id":"W4385613208","doi":"10.1053/j.gastro.2023.07.024","title":"Endoscopic Ultrasound-Guided Biliary Drainage of First Intent With a Lumen-Apposing Metal Stent vs Endoscopic Retrograde Cholangiopancreatography in Malignant Distal Biliary Obstruction: A Multicenter Randomized Controlled Study (ELEMENT Trial)","year":2023,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Gallbladder and Bile Duct Disorders","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Jewish General Hospital; University of Alberta Hospital; Ottawa Hospital; Alberta Hospital Edmonton; University of Calgary; Vancouver General Hospital; Hôpital Charles-Le Moyne; University of Toronto; St. Paul's Hospital; Centre Hospitalier de l’Université de Montréal; McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Boston Scientific Corporation; American Society for Gastrointestinal Endoscopy","keywords":"Medicine; Endoscopic retrograde cholangiopancreatography; Endoscopic ultrasound; Stent; Randomized controlled trial; Clinical endpoint; Radiology; Surgery; Pancreatitis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002676998,0.001297522,0.002706546,0.0003875356,0.0003915521,0.00125701,0.0008518476,0.001883044,0.003396157],"category_scores_gemma":[0.003730382,0.0005726453,0.002354383,0.000468783,0.001069528,0.0007868569,0.0005067311,0.001489445,0.0003494976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008951908,"about_ca_system_score_gemma":0.00124181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001917515,"about_ca_topic_score_gemma":0.003197984,"domain_scores_codex":[0.9986619,0.0008766667,0.0001033729,0.0001532036,0.00007302506,0.0001318832],"domain_scores_gemma":[0.9983259,0.0006330188,0.0004960573,0.0001300103,0.000101862,0.0003132031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9896166,0.002067898,0.001335446,0.0003973561,0.001103027,0.00002309623,0.00002795281,0.0001183869,0.0007002267,0.00005920726,0.0001861935,0.00436459],"study_design_scores_gemma":[0.9632062,0.03229411,0.002423121,0.00005345865,0.001240517,0.00002561542,0.00002107447,0.000222639,0.0001945321,0.00006447059,0.0002443565,0.000009850632],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925755,0.004483092,0.000249003,0.00054279,0.0002837912,0.001080663,0.0002660706,0.0000282346,0.0004909452],"genre_scores_gemma":[0.9906378,0.002542123,0.001374964,0.0007842555,0.0007581865,0.00232274,0.000545186,0.0000106366,0.001024153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003396157,"threshold_uncertainty_score":0.01415747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01323528298271081,"score_gpt":0.2568315592335889,"score_spread":0.243596276250878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}