{"id":"W4385615101","doi":"10.1101/2023.08.05.552141","title":"Enterovirus-A71 exploits Rab11 to recruit chaperones for virus morphogenesis","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"National Medical Research Council; Medical Research Council; Nanyang Technological University; National Research Foundation","keywords":"Viral replication; Biology; GTPase; Rab; Virology; Viral protein; Enterovirus 71; Viral entry; Cell biology; Chaperone (clinical); Morphogenesis; Host factor; Virus; Immunoprecipitation; Enterovirus; Genetics; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009770552,0.0002812495,0.0001321443,0.0001562013,0.0001618514,0.000309346,0.0001094717,0.0002663824,0.001297922],"category_scores_gemma":[0.0001137859,0.0001070182,0.000183019,0.0001283873,0.0001125354,0.000138284,0.0002550468,0.0002664867,0.001082333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002845793,"about_ca_system_score_gemma":0.0001388188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005080061,"about_ca_topic_score_gemma":0.0007158581,"domain_scores_codex":[0.9999443,0.000008120945,0.000003269096,0.00001033259,0.00001089985,0.00002319135],"domain_scores_gemma":[0.9999635,0.000006453881,0.000005531722,0.0000073649,0.000005676313,0.00001139496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000769476,0.00001794818,0.0004912533,0.00002565308,0.000004369842,0.0001276151,0.00001003896,0.0000976446,0.9974223,0.000299113,0.0002096395,0.001217505],"study_design_scores_gemma":[0.00001484619,0.00006979972,0.005689184,0.00000738561,0.000008943981,0.0004434596,0.0000430631,0.003310004,0.9844919,0.0001990834,0.005717456,0.000004916129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922923,0.0008395292,0.003366051,0.0001328136,0.00004614613,0.00001554981,0.000265186,0.0001405683,0.002901785],"genre_scores_gemma":[0.9889436,0.0004818241,0.002913884,0.00004803124,0.00001016162,0.00001350701,0.0009579036,0.00004650023,0.006584693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001297922,"threshold_uncertainty_score":0.00434196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08150728962638382,"score_gpt":0.3114797221900769,"score_spread":0.229972432563693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}