{"id":"W4385622022","doi":"10.17159/sajs.2023/13745","title":"In vitro cytotoxic and apoptotic activity of the Mauritian marine sponge Neopetrosia exigua","year":2023,"lang":"en","type":"article","venue":"South African Journal of Science","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Institute of Genetics; Mauritius Research Council","keywords":"Apoptosis; Superoxide dismutase; Reactive oxygen species; Poly ADP ribose polymerase; Cytotoxic T cell; Biology; Catalase; Cytotoxicity; Biochemistry; Cancer cell; Molecular biology; Chemistry; Oxidative stress; In vitro; Enzyme; Cancer; Polymerase","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000835353,0.00007731964,0.0001336108,0.0001507694,0.000073703,0.00001728576,0.0003846974,0.00003014726,0.000006895056],"category_scores_gemma":[0.0003247697,0.00005075698,0.00005135468,0.000847774,0.0005984901,0.00001660931,0.0003507345,0.0001516121,6.779354e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001372662,"about_ca_system_score_gemma":0.0001528402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001460329,"about_ca_topic_score_gemma":0.00000702086,"domain_scores_codex":[0.9991407,0.000041843,0.0001734955,0.0001754128,0.0002542155,0.000214317],"domain_scores_gemma":[0.9994279,0.00001034002,0.000185836,0.0001954415,0.00009718994,0.00008334718],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001159065,0.00001409373,0.004396015,0.00001203685,0.000003776575,0.000006252435,0.0001778716,0.00001443345,0.9931888,0.00001729894,0.00002861534,0.002024878],"study_design_scores_gemma":[0.00035248,0.0001962051,0.246643,0.00001629059,0.000007663738,0.00007290503,0.0003657894,0.00007707562,0.7517326,0.0001646453,0.0002819361,0.00008932479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987161,0.00006796804,0.000003921007,0.0006504626,0.0001760529,0.00006572788,0.000005489914,0.000001471999,0.0003128092],"genre_scores_gemma":[0.9993694,0.00003733195,0.0001562614,0.00004143545,0.00008890104,5.571078e-7,3.49839e-7,0.000004732075,0.0003010298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.242247,"threshold_uncertainty_score":0.2205162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008583242139681369,"score_gpt":0.2376870608496552,"score_spread":0.2291038187099738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}