{"id":"W4385622022","doi":"10.17159/sajs.2023/13745","title":"In vitro cytotoxic and apoptotic activity of the Mauritian marine sponge Neopetrosia exigua","year":2023,"lang":"en","type":"article","venue":"South African Journal of Science","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Institute of Genetics; Mauritius Research Council","keywords":"Apoptosis; Superoxide dismutase; Reactive oxygen species; Poly ADP ribose polymerase; Cytotoxic T cell; Biology; Catalase; Cytotoxicity; Biochemistry; Cancer cell; Molecular biology; Chemistry; Oxidative stress; In vitro; Enzyme; Cancer; Polymerase","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007925646,0.0002920815,0.0001638639,0.0002527177,0.0001182199,0.0001231887,0.00009007049,0.0001389021,0.001029408],"category_scores_gemma":[0.0001545577,0.00007163783,0.0002038535,0.000157083,0.0001141929,0.0001134434,0.0001598339,0.0002240337,0.0001376809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008926741,"about_ca_system_score_gemma":0.0001205913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007430809,"about_ca_topic_score_gemma":0.001334379,"domain_scores_codex":[0.9999484,0.0000103428,0.000006316511,0.000005968728,0.00001873958,0.00001021265],"domain_scores_gemma":[0.9999243,0.00002007729,0.00002025828,0.000007001907,0.00001293721,0.00001535943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002327452,0.00003176448,0.0008578792,0.00016784,0.00001154311,0.0002164039,0.00002784645,0.0001061888,0.9948785,0.00002423062,0.000033311,0.003411858],"study_design_scores_gemma":[0.00003223068,0.003039328,0.04780747,0.00004259102,0.00009134495,0.001656436,0.0001268747,0.0004251779,0.941164,0.0000799115,0.005521929,0.00001273728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938333,0.003562551,0.0004166216,0.00006142163,0.00001425493,0.00001962756,0.0002632523,0.00001734293,0.001811624],"genre_scores_gemma":[0.9944712,0.002182907,0.0006988101,0.00005051253,0.00001432953,0.00002312725,0.0005972255,0.000005213921,0.001956628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001029408,"threshold_uncertainty_score":0.003443718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008583242139681369,"score_gpt":0.2376870608496552,"score_spread":0.2291038187099738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}