{"id":"W4385641417","doi":"10.7150/jca.85966","title":"Combined Use of Immune Checkpoint Inhibitors and Phytochemicals as a Novel Therapeutic Strategy against Cancer","year":2023,"lang":"en","type":"review","venue":"Journal of Cancer","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"China Postdoctoral Science Foundation; National Natural Science Foundation of China; Harbin Medical University","keywords":"Medicine; Adverse effect; Rash; Immune system; Cancer; Oncology; Immune checkpoint; Combination therapy; Immunology; Pharmacology; Immunotherapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003373982,0.0006642422,0.001132698,0.002031987,0.0002311668,0.0006620529,0.0005287098,0.0007069936,0.003239124],"category_scores_gemma":[0.000338016,0.00022036,0.0006364869,0.001382204,0.0002482521,0.0007285005,0.0004598585,0.001277761,0.001176119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003423146,"about_ca_system_score_gemma":0.0005684225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005449909,"about_ca_topic_score_gemma":0.001407212,"domain_scores_codex":[0.9998552,0.00002339722,0.00001972962,0.00002749326,0.0000578055,0.00001632516],"domain_scores_gemma":[0.9998828,0.00005680417,0.00001818922,0.000004817816,0.00002724868,0.00001004475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001483761,0.0001862068,0.0002097034,0.02658536,0.0001927478,0.0002366914,0.00004982612,0.0003707788,0.007005632,0.002238845,0.01290208,0.9498738],"study_design_scores_gemma":[0.00004997427,0.0003626313,0.001600988,0.003637089,0.0003712476,0.001646573,0.00005570281,0.0001748357,0.002713792,0.001429275,0.9879321,0.00002569743],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004581384,0.9980022,0.0001717233,0.0001464819,0.0001412704,0.000009927833,0.00002850141,0.00001045965,0.001031362],"genre_scores_gemma":[0.001686981,0.9971955,0.0002628643,0.0001471929,0.00009430942,0.00001027184,0.00004208938,0.000001586257,0.0005592206],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003239124,"threshold_uncertainty_score":0.01083595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1069065336602923,"score_gpt":0.3969457465237053,"score_spread":0.290039212863413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}