{"id":"W4385644673","doi":"10.1097/01.hs9.0000967692.36989.7b","title":"S195: IDECABTAGENE VICLEUCEL (IDE-CEL) VS STANDARD REGIMENS IN PATIENTS WITH TRIPLE-CLASS–EXPOSED (TCE) RELAPSED AND REFRACTORY MULTIPLE MYELOMA (RRMM): A KARMMA-3 ANALYSIS IN HIGH-RISK SUBGROUPS","year":2023,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Daratumumab; Medicine; Internal medicine; Regimen; Oncology; Refractory (planetary science); Lenalidomide; Population; Multiple myeloma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001154818,0.000489327,0.001291,0.0009609066,0.0001362959,0.00006307651,0.0002287565,0.0003381476,0.00164176],"category_scores_gemma":[0.0004892182,0.0004238065,0.000210273,0.00459051,0.0001973973,0.000223168,0.0001691601,0.0009342292,0.00007390177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007132029,"about_ca_system_score_gemma":0.0002700971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001353066,"about_ca_topic_score_gemma":0.01166694,"domain_scores_codex":[0.9952936,0.0004173972,0.0008641935,0.001074662,0.001359688,0.000990457],"domain_scores_gemma":[0.9973448,0.000576716,0.0002807572,0.001093841,0.000262804,0.0004411118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01392187,0.0005299776,0.9605591,0.000158707,0.0006861307,0.0005541751,0.001625746,0.000125345,0.009297656,0.00001025337,0.001208904,0.01132213],"study_design_scores_gemma":[0.03335174,0.002102287,0.9538229,0.0002324219,0.0003670098,0.000004340199,0.001161423,0.00131833,0.004096649,0.0000466182,0.003000637,0.0004956046],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966727,0.0003373859,0.00003156032,0.0003601463,0.00008912034,0.001594794,0.000133459,0.0001955156,0.0005852845],"genre_scores_gemma":[0.9921986,0.0004018853,0.000644632,0.0001285319,0.00006774072,0.0001246519,0.0003651806,0.0001394259,0.00592933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01942987,"threshold_uncertainty_score":0.9998214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01265303085756406,"score_gpt":0.2517735670351252,"score_spread":0.2391205361775612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}