{"id":"W4385644673","doi":"10.1097/01.hs9.0000967692.36989.7b","title":"S195: IDECABTAGENE VICLEUCEL (IDE-CEL) VS STANDARD REGIMENS IN PATIENTS WITH TRIPLE-CLASS–EXPOSED (TCE) RELAPSED AND REFRACTORY MULTIPLE MYELOMA (RRMM): A KARMMA-3 ANALYSIS IN HIGH-RISK SUBGROUPS","year":2023,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Daratumumab; Medicine; Internal medicine; Regimen; Oncology; Refractory (planetary science); Lenalidomide; Population; Multiple myeloma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009986203,0.0002543658,0.0007722783,0.0002872125,0.0001571361,0.0007546113,0.0003402381,0.0005077471,0.002683139],"category_scores_gemma":[0.0007418784,0.0001251789,0.001680365,0.0002654694,0.0002603117,0.0004103624,0.0003061333,0.0007980045,0.0002749924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007484676,"about_ca_system_score_gemma":0.0005034157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005686971,"about_ca_topic_score_gemma":0.002019662,"domain_scores_codex":[0.9995957,0.0001650469,0.00002845209,0.00007397497,0.00005007765,0.00008680943],"domain_scores_gemma":[0.9995018,0.0001473368,0.0001403624,0.00004255995,0.00001941244,0.0001485177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7308421,0.003788345,0.1410861,0.0005218867,0.005555495,0.0002705748,0.0001880425,0.001686837,0.01039796,0.000314715,0.002520873,0.102827],"study_design_scores_gemma":[0.09424422,0.2750821,0.598251,0.0002577814,0.007328889,0.001337587,0.0003443169,0.006508693,0.005331888,0.0009261846,0.01031499,0.00007218052],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969709,0.001694151,0.00008261615,0.00009850362,0.00003862409,0.00005409446,0.0003715641,0.00001058239,0.0006788946],"genre_scores_gemma":[0.9981626,0.0003512096,0.0001513158,0.0002035946,0.00005756956,0.00005885082,0.0005580704,0.00000334074,0.0004534722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002683139,"threshold_uncertainty_score":0.008975983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01265303085756406,"score_gpt":0.2517735670351252,"score_spread":0.2391205361775612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}