{"id":"W4385654848","doi":"10.3390/toxics11080682","title":"Drosophila as a Robust Model System for Assessing Autophagy: A Review","year":2023,"lang":"en","type":"review","venue":"Toxics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Population and Public Health; University of Ottawa","funders":"US-UK Fulbright Commission","keywords":"Autophagy; Drosophila melanogaster; Biology; Model organism; Drosophila (subgenus); Cell biology; Organism; Mechanism (biology); Yeast; Genetic screen; Senescence; Programmed cell death; Computational biology; Cellular stress response; ATG8; Fight-or-flight response; Genetics; Phenotype; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005256983,0.001041638,0.001227243,0.00324002,0.000249208,0.0008176527,0.0007756755,0.0008931818,0.002084291],"category_scores_gemma":[0.0005368254,0.0003363538,0.0005156145,0.002585091,0.0004695177,0.001321179,0.0005079676,0.001316273,0.001587767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005852456,"about_ca_system_score_gemma":0.0007971738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001373735,"about_ca_topic_score_gemma":0.001795957,"domain_scores_codex":[0.9998209,0.00002685797,0.0000339444,0.00004189096,0.00006466548,0.00001173908],"domain_scores_gemma":[0.9997057,0.000134726,0.00004879778,0.00001136229,0.000069142,0.00003024355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007729085,0.00008157937,0.0002598825,0.02883532,0.0001150165,0.0001780896,0.00005618799,0.0004606328,0.005630708,0.004951592,0.03463927,0.9247144],"study_design_scores_gemma":[0.000011659,0.0001124793,0.001050899,0.003765927,0.0001604657,0.0009623406,0.00003926017,0.0001222659,0.001285821,0.001590266,0.9908696,0.00002899815],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001425686,0.9981298,0.0002472681,0.0001273553,0.000155581,0.000007507334,0.00004450055,0.00001147688,0.001134003],"genre_scores_gemma":[0.0006315804,0.998133,0.0004849845,0.0001466429,0.00009531519,0.00001188311,0.00007541231,0.000003082054,0.0004181562],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00324002,"threshold_uncertainty_score":0.006972611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2033994764000824,"score_gpt":0.4459670133350339,"score_spread":0.2425675369349515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}