{"id":"W4385665137","doi":"10.3389/fpls.2023.1233666","title":"An oligosaccharyltransferase from Leishmania donovani increases the N-glycan occupancy on plant-produced IgG1","year":2023,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Medicago (Canada)","funders":"School of Medicine, Duke University; National Institutes of Health; Bundesministerium für Digitalisierung und Wirtschaftsstandort; Österreichische Forschungsförderungsgesellschaft; National Institute of Allergy and Infectious Diseases; EQUIPMENT BOKU VIENNA INSTITUTE OF BIOTECHNOLOGY; Standortagentur Tirol; Universität für Bodenkultur Wien; Austrian Science Fund; Amt der NÖ Landesregierung","keywords":"Glycan; Occupancy; Leishmania donovani; Biology; Leishmania; Leishmaniasis; Immunology; Glycoprotein; Ecology; Biochemistry; Visceral leishmaniasis; Parasite hosting; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001241203,0.0004081908,0.0002271757,0.0001263766,0.0001003229,0.0002966379,0.0001669443,0.0001869738,0.0006593422],"category_scores_gemma":[0.00009769677,0.0001280386,0.0002256157,0.0001451039,0.0001844169,0.0001413686,0.0002630732,0.0004303244,0.000242274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003865661,"about_ca_system_score_gemma":0.0001991298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001132269,"about_ca_topic_score_gemma":0.001754594,"domain_scores_codex":[0.9999117,0.00001553322,0.000006583844,0.00002108828,0.00001794314,0.00002712798],"domain_scores_gemma":[0.9999259,0.00001396563,0.00002404128,0.000008704302,0.000009400292,0.00001799083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002257835,0.000005492244,0.00004210558,0.00001247268,0.00000163958,0.000009584565,0.000004688367,0.0000129249,0.9996411,0.00001617975,0.000005652521,0.0002255991],"study_design_scores_gemma":[0.00000484976,0.00007927282,0.001451352,0.000002907097,0.000009656182,0.00006160576,0.00001182597,0.0002748515,0.9969742,0.00001187927,0.00111509,0.00000241414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968978,0.0004392382,0.001677838,0.00004874558,0.00001103961,0.00001286671,0.0001408354,0.00006196003,0.0007095438],"genre_scores_gemma":[0.993055,0.0004514647,0.002806026,0.0000716427,0.000003959349,0.00001755539,0.0006640635,0.00005332265,0.002876864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001132269,"threshold_uncertainty_score":0.002804756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01336859557232576,"score_gpt":0.2486991054644847,"score_spread":0.235330509892159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}