{"id":"W4385665137","doi":"10.3389/fpls.2023.1233666","title":"An oligosaccharyltransferase from Leishmania donovani increases the N-glycan occupancy on plant-produced IgG1","year":2023,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Medicago (Canada)","funders":"School of Medicine, Duke University; National Institutes of Health; Bundesministerium für Digitalisierung und Wirtschaftsstandort; Österreichische Forschungsförderungsgesellschaft; National Institute of Allergy and Infectious Diseases; EQUIPMENT BOKU VIENNA INSTITUTE OF BIOTECHNOLOGY; Standortagentur Tirol; Universität für Bodenkultur Wien; Austrian Science Fund; Amt der NÖ Landesregierung","keywords":"Glycan; Occupancy; Leishmania donovani; Biology; Leishmania; Leishmaniasis; Immunology; Glycoprotein; Ecology; Biochemistry; Visceral leishmaniasis; Parasite hosting; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003461552,0.0001582384,0.0001362428,0.0001226702,0.000293926,0.00006544132,0.0008762455,0.0000682891,0.000007032102],"category_scores_gemma":[0.00003596113,0.0001176815,0.00003710216,0.0005184688,0.0002647463,0.00001682399,0.00004102596,0.0001290189,0.00002152697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001883415,"about_ca_system_score_gemma":0.0001520325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004241789,"about_ca_topic_score_gemma":0.0003327495,"domain_scores_codex":[0.9984857,0.00003953256,0.0001831456,0.0006406853,0.000252988,0.0003979711],"domain_scores_gemma":[0.999186,0.00002515121,0.0000370759,0.0006110476,0.00001933548,0.0001213633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002963465,0.0001773267,0.0472258,0.00000631708,0.00002602457,0.00003371631,0.000252626,0.0002667516,0.9071379,0.0005805475,0.04078502,0.00321168],"study_design_scores_gemma":[0.001357252,0.0003931832,0.331636,0.00007869554,0.0000370934,0.00004448084,0.0009467716,0.004042833,0.6180636,0.001309513,0.04123964,0.0008509731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942737,0.0001312814,0.0009123381,0.0002751936,0.0004499745,0.0002433238,0.003523946,0.00004533135,0.0001449519],"genre_scores_gemma":[0.9971393,0.0004256393,0.0004363509,0.0004090202,0.0001600083,0.00004426065,0.001336132,0.00001167241,0.00003757219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2890742,"threshold_uncertainty_score":0.4798913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01336859557232576,"score_gpt":0.2486991054644847,"score_spread":0.235330509892159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}