{"id":"W4385667055","doi":"10.1097/01.hs9.0000968868.83152.da","title":"P490: UPDATED SURVIVAL, BLOOD COUNT RECOVERY AND SAFETY RESULTS FROM THE AGILE STUDY IN PATIENTS WITH ACUTE MYELOID LEUKEMIA TREATED WITH IVOSIDENIB + AZACITIDINE COMPARED TO PLACEBO + AZACITIDINE","year":2023,"lang":"en","type":"article","venue":"HemaSphere","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Servier; Agios Pharmaceuticals","keywords":"Medicine; Internal medicine; IDH1; Isocitrate dehydrogenase; Myeloid leukemia; Placebo; Azacitidine; Gastroenterology; Clinical endpoint; Randomized controlled trial; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001899497,0.0008863739,0.002019003,0.0004125644,0.000196183,0.000921076,0.0006818628,0.0008859053,0.002373985],"category_scores_gemma":[0.001526505,0.0002873435,0.001711432,0.0005616902,0.0005831262,0.0006944435,0.0004817273,0.001780368,0.0003413575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003739175,"about_ca_system_score_gemma":0.0005197568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004409382,"about_ca_topic_score_gemma":0.0009401664,"domain_scores_codex":[0.9992108,0.0004704944,0.00005291819,0.0001051264,0.0001003956,0.00006026577],"domain_scores_gemma":[0.998389,0.0004349506,0.0005700316,0.0001030177,0.00008034759,0.0004227934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8973477,0.003921107,0.02986276,0.000641835,0.004812744,0.00009124172,0.00008583185,0.0009413036,0.007418699,0.00008274167,0.001767483,0.05302641],"study_design_scores_gemma":[0.5949854,0.2174106,0.1722634,0.000121134,0.007923705,0.0003768017,0.00009047679,0.001331785,0.001864135,0.0002879287,0.003269564,0.0000749762],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911616,0.004914353,0.0002719635,0.0002898155,0.00007760715,0.0003429093,0.001963966,0.00004111477,0.0009366625],"genre_scores_gemma":[0.9917071,0.002450765,0.0006789566,0.0005174651,0.0002570115,0.0005324048,0.003209368,0.00001626388,0.0006305474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002373985,"threshold_uncertainty_score":0.01004559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01716513377877496,"score_gpt":0.2578016838729831,"score_spread":0.2406365500942082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}