{"id":"W4385667659","doi":"10.1097/01.hs9.0000972428.19857.ae","title":"P1385: DISTINCT RATES OF ICANS BUT SIMILAR CYTOKINE SIGNATURES BETWEEN TWO CD19-CAR T CELL THERAPIES: LISOCABTAGENE MARALEUCEL AND AXICABTAGENE CILOLEUCEL","year":2023,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cytokine release syndrome; Medicine; Oncology; Chimeric antigen receptor; Internal medicine; Immunotherapy; Immunology; Cytokine; Immune system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001871305,0.0001488714,0.0002468193,0.0001633616,0.0001299152,0.0002933594,0.0001788171,0.0002953812,0.002939643],"category_scores_gemma":[0.000467053,0.00008270905,0.0002214679,0.0001502549,0.0001826456,0.0002369972,0.0001842127,0.0005672446,0.0005371476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003651623,"about_ca_system_score_gemma":0.0001864656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003769734,"about_ca_topic_score_gemma":0.0004321968,"domain_scores_codex":[0.9998646,0.00001809454,0.0000103433,0.00004095139,0.00003049234,0.00003552497],"domain_scores_gemma":[0.9997093,0.00005990443,0.00008787194,0.00002701969,0.00002620755,0.00008967481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.03205935,0.002290258,0.3740785,0.0002020319,0.000209443,0.004619713,0.0004324634,0.0009484086,0.4584122,0.0005831086,0.002748809,0.1234157],"study_design_scores_gemma":[0.0008469788,0.02163597,0.8740679,0.00002175108,0.0001417102,0.01132043,0.0003298823,0.002204295,0.08257015,0.0003354346,0.006499557,0.0000259352],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988678,0.0002000516,0.0001481867,0.0000295777,0.000004947136,0.00001686962,0.0001821384,0.000009132247,0.0005413145],"genre_scores_gemma":[0.9986638,0.00004945875,0.0001003529,0.00004073269,0.000006304012,0.00001979389,0.0005895401,0.000004635011,0.0005253551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002939643,"threshold_uncertainty_score":0.009834051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04156970555081718,"score_gpt":0.3260492216013925,"score_spread":0.2844795160505754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}