{"id":"W4385667659","doi":"10.1097/01.hs9.0000972428.19857.ae","title":"P1385: DISTINCT RATES OF ICANS BUT SIMILAR CYTOKINE SIGNATURES BETWEEN TWO CD19-CAR T CELL THERAPIES: LISOCABTAGENE MARALEUCEL AND AXICABTAGENE CILOLEUCEL","year":2023,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cytokine release syndrome; Medicine; Oncology; Chimeric antigen receptor; Internal medicine; Immunotherapy; Immunology; Cytokine; Immune system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006374232,0.000495612,0.001013012,0.0002064024,0.000174911,0.00004954295,0.0003427007,0.0002882271,0.004989963],"category_scores_gemma":[0.0001277828,0.0004203563,0.000285541,0.0009566582,0.0004223391,0.0001019716,0.000253335,0.000632237,0.0001105832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009310389,"about_ca_system_score_gemma":0.0001992187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002679382,"about_ca_topic_score_gemma":0.00008544864,"domain_scores_codex":[0.9967234,0.0001894506,0.0006239751,0.0007494339,0.0008838314,0.0008299563],"domain_scores_gemma":[0.997607,0.0006709027,0.0001844862,0.0008707916,0.0002377089,0.000429123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004924454,0.0001982562,0.06786856,0.000787297,0.0004004277,0.0002340377,0.0008432514,0.00003473311,0.9112409,0.00004502271,0.006858112,0.01099697],"study_design_scores_gemma":[0.007732312,0.001438823,0.1737811,0.0003804352,0.0003878665,0.00002847544,0.002585777,0.0006901717,0.7672604,0.0005453153,0.04431117,0.0008581014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863257,0.005020853,0.00009541697,0.0012964,0.0001042181,0.0009147277,0.0003237053,0.0002512426,0.005667684],"genre_scores_gemma":[0.9655217,0.001721321,0.0006285492,0.0002241179,0.000612508,0.00006822858,0.0002440272,0.0001544925,0.03082509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1439805,"threshold_uncertainty_score":0.9998248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04156970555081718,"score_gpt":0.3260492216013925,"score_spread":0.2844795160505754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}