{"id":"W4385686230","doi":"10.4049/jimmunol.210.supp.238.04","title":"Suppression of IGRP-specific CD8 T cells following induction of tolerance to a Hybrid Insulin Peptide CD4 neoepitope","year":2023,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"NOD mice; CD8; Biology; Cytotoxic T cell; Immunology; Spleen; Antigen; Immune system; Autoimmunity; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001190103,0.0004224058,0.0002965607,0.0001515375,0.00008307052,0.0002110858,0.0001571856,0.0002789682,0.00114231],"category_scores_gemma":[0.0001066778,0.00009975523,0.0002079577,0.00008721726,0.0002002791,0.0001303295,0.0001671091,0.0007882828,0.000266914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001358201,"about_ca_system_score_gemma":0.0001162605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001487982,"about_ca_topic_score_gemma":0.000180404,"domain_scores_codex":[0.9998037,0.00003050316,0.00001589174,0.00004161653,0.00004084831,0.0000673947],"domain_scores_gemma":[0.999871,0.00002143949,0.00003766496,0.00001770967,0.00001240759,0.00003981359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000204615,0.00007533426,0.0001142328,0.00002769229,0.000002526727,0.00003405644,0.00001299997,0.00004546668,0.9983978,0.00002323562,0.00001976523,0.00104239],"study_design_scores_gemma":[0.00005316167,0.002381597,0.003045525,0.000008395137,0.00001815911,0.0001943796,0.00003223152,0.0009015288,0.9923436,0.00002742849,0.0009902206,0.000003737946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982337,0.0002507889,0.0006279919,0.00002305343,0.00002365883,0.0000183294,0.00007258834,0.00005035922,0.0006996325],"genre_scores_gemma":[0.9976168,0.0001234949,0.0005152634,0.00005062072,0.00001676042,0.00004162637,0.0001317384,0.00001174641,0.001492083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00114231,"threshold_uncertainty_score":0.003821433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008140992877916196,"score_gpt":0.2281461793845186,"score_spread":0.2200051865066024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}