{"id":"W4385686612","doi":"10.4049/jimmunol.210.supp.155.07","title":"Trisomy 8-associated Autoinflammatory Disease (TRIAD) is Characterized by Dysregulated Myeloid Cells","year":2023,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Immunology; Myeloid; Trisomy 8; Biology; Trisomy; Bone marrow; Karyotype; Genetics; Chromosome; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008655938,0.0002986532,0.0001766397,0.0006254656,0.0002285348,0.0001692558,0.0001070622,0.0001817469,0.002055055],"category_scores_gemma":[0.0002843292,0.00009268396,0.0001314761,0.0002877871,0.0002078308,0.00009247605,0.0002787766,0.0001741583,0.0002262209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001116924,"about_ca_system_score_gemma":0.00006738476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003571449,"about_ca_topic_score_gemma":0.0005265393,"domain_scores_codex":[0.9998778,0.00001943504,0.00001371674,0.00004042114,0.00002343451,0.00002515832],"domain_scores_gemma":[0.9998341,0.00003244425,0.00007832032,0.00000936082,0.00001229834,0.00003357985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001140056,0.00006868163,0.3981716,0.00009971908,0.00005769801,0.01568806,0.0004843155,0.0001317805,0.5725174,0.000229798,0.0002893884,0.01112166],"study_design_scores_gemma":[0.00004706991,0.0009420297,0.8530597,0.00003026596,0.00008417922,0.1035034,0.0004769069,0.0006361649,0.03912899,0.0002588445,0.001817676,0.00001463576],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992982,0.000151597,0.0002039956,0.00001313993,0.00000196258,0.000005965388,0.0000906713,0.000008971419,0.0002255202],"genre_scores_gemma":[0.9994175,0.00008099026,0.0002253418,0.00001520801,0.000004665541,0.000006159895,0.0001136736,0.000002584634,0.0001337746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002055055,"threshold_uncertainty_score":0.0068748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005655252451449187,"score_gpt":0.2136639468945176,"score_spread":0.2080086944430685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}