{"id":"W4385687487","doi":"10.4049/jimmunol.210.supp.173.02","title":"CAR Tregs protect alloimmune islets against autoimmune destruction","year":2023,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Immunology; Polyclonal antibodies; Autoimmunity; Islet; Antigen; Biology; Transplantation; Bystander effect; NOD mice; Immune system; Medicine; Insulin; Endocrinology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002094892,0.0005347815,0.0004154136,0.0002689956,0.0001320116,0.0003137785,0.0002110291,0.0003742856,0.002759228],"category_scores_gemma":[0.00009606018,0.000171055,0.0002722185,0.00008418127,0.0001588549,0.0002185615,0.0001821892,0.001109758,0.0005427157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001162728,"about_ca_system_score_gemma":0.0002094002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001727871,"about_ca_topic_score_gemma":0.0002296996,"domain_scores_codex":[0.9998259,0.00001935288,0.00001265407,0.00003839431,0.00004482829,0.00005891472],"domain_scores_gemma":[0.9998577,0.00001559573,0.00002754382,0.00002912911,0.00001421051,0.00005591906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001560685,0.0005732686,0.0003509568,0.00007271554,0.00002548321,0.00009864238,0.00001754049,0.0002053624,0.9904851,0.0001666062,0.0003498323,0.006093803],"study_design_scores_gemma":[0.0004844141,0.006832289,0.005922588,0.00003286645,0.00006531824,0.0007813422,0.0000575512,0.002210209,0.9767353,0.0002878965,0.006577542,0.00001264994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933263,0.00157249,0.001809011,0.0001185731,0.0001767863,0.00003764711,0.0002797372,0.0003273404,0.00235216],"genre_scores_gemma":[0.9935049,0.0004860727,0.0008452387,0.0001764205,0.00006136182,0.00005164966,0.0004334574,0.00003468739,0.004406114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002759228,"threshold_uncertainty_score":0.009230494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01305448951645827,"score_gpt":0.2313889990586588,"score_spread":0.2183345095422005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}