{"id":"W4385697985","doi":"10.1097/01.hs9.0000974984.02232.24","title":"PB2045: USE OF ANAKINRA IN THE TREATMENT OF ADULT HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS: A SYSTEMATIC REVIEW","year":2023,"lang":"en","type":"review","venue":"HemaSphere","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; McMaster University","funders":"","keywords":"Anakinra; Hemophagocytic lymphohistiocytosis; Medicine; Macrophage activation syndrome; Pediatrics; Retrospective cohort study; Internal medicine; Cytokine storm; Primary immunodeficiency; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00240289,0.0008314458,0.005347959,0.006056798,0.0003885497,0.001405108,0.001254219,0.001425014,0.00453204],"category_scores_gemma":[0.01014236,0.0005020095,0.004330476,0.007911853,0.0005212024,0.001304278,0.0008013556,0.000626487,0.0003127917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001673742,"about_ca_system_score_gemma":0.004489252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005099269,"about_ca_topic_score_gemma":0.01377834,"domain_scores_codex":[0.9975553,0.0006076123,0.001167873,0.0002127417,0.0003625318,0.00009384345],"domain_scores_gemma":[0.9916095,0.005509403,0.00192297,0.00009032736,0.0007421837,0.000125447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0003355677,0.00001451987,0.0007563077,0.9516922,0.00437321,0.00008726115,0.0000842744,0.00005880177,0.0001844069,0.00008180277,0.001361509,0.04097016],"study_design_scores_gemma":[0.0004803271,0.0004225372,0.008239526,0.902176,0.06417863,0.0006881779,0.0002437552,0.00008775942,0.0002313811,0.0001594025,0.02305979,0.00003266386],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001017797,0.9982001,0.00003526899,0.00009883145,0.00004896245,0.00008389829,0.0003118552,0.00000382066,0.0001993878],"genre_scores_gemma":[0.009009731,0.9900599,0.0001713965,0.0002698977,0.000060091,0.0001614342,0.0001936137,0.000002096522,0.00007178465],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006056798,"threshold_uncertainty_score":0.01516116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1231056789853798,"score_gpt":0.3872002908171469,"score_spread":0.2640946118317671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}