{"id":"W4385707526","doi":"10.17975/sfj-2023-006","title":"Comparison of Non-viral Delivery Vehicles for CRISPR/Cas9 Therapies","year":2023,"lang":"en","type":"article","venue":"STEM Fellowship Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Cas9; Viral vector; Computational biology; SAFER; Gene delivery; Genetic enhancement; Computer science; Biology; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000304873,0.0001264038,0.0001970883,0.00007864702,0.0001052459,0.00002967806,0.0001868785,0.0001002778,0.000006859364],"category_scores_gemma":[0.00001832033,0.0001147348,0.0001781043,0.00008511447,0.00004032571,0.000003993887,0.00004811121,0.0001101579,0.00000697523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007822736,"about_ca_system_score_gemma":0.00004506808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002432104,"about_ca_topic_score_gemma":0.000005480264,"domain_scores_codex":[0.9991344,0.00002686628,0.000296438,0.0001489218,0.000133547,0.0002598005],"domain_scores_gemma":[0.9995261,0.00003187611,0.0001009304,0.0001588424,0.0001069436,0.00007525324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001191161,0.00003618509,0.0135324,0.00007251465,0.0001302571,0.000003346493,0.0006104182,0.002775582,0.956799,0.00001598748,0.0120672,0.013838],"study_design_scores_gemma":[0.001024463,0.0006728707,0.01153752,0.00005717777,0.00004706337,0.00003307671,0.002858735,0.003778397,0.9571116,0.0001357388,0.0224788,0.0002645518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788592,0.00254051,0.01778676,0.00009983331,0.000414989,0.0001251735,0.00001551209,0.00001353812,0.00014443],"genre_scores_gemma":[0.997666,0.0003120791,0.0008950975,0.00002996959,0.0004152443,0.000009124718,0.0000186226,0.00002629464,0.0006275862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01880673,"threshold_uncertainty_score":0.467875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02859987965906615,"score_gpt":0.360801811950905,"score_spread":0.3322019322918389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}