{"id":"W4385719099","doi":"10.1182/blood.2022019586","title":"Genotype, oxidase status, and preceding infection or autoinflammation do not affect allogeneic HCT outcomes for CGD","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine; Alberta Children's Hospital; University of Calgary; CancerCare Manitoba; Montreal Clinical Research Institute; Hospital for Sick Children; University of Toronto","funders":"NHLBI Division of Intramural Research; National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; Office of Naval Research; Health Resources and Services Administration; National Cancer Institute; U.S. Department of Health and Human Services; National Institutes of Health; National Heart, Lung, and Blood Institute; St. Baldrick's Foundation","keywords":"Medicine; Internal medicine; Chronic granulomatous disease; Transplantation; Melphalan; Hematopoietic stem cell transplantation; Retrospective cohort study; Surgery; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004179717,0.000153751,0.0002392063,0.0002833866,0.0002553212,0.0004123783,0.0001802827,0.0002287528,0.00104649],"category_scores_gemma":[0.001473187,0.00008950019,0.0003269989,0.0003220783,0.0001888806,0.000239427,0.0002839992,0.0003533402,0.0001269779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002240399,"about_ca_system_score_gemma":0.0002078167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001061709,"about_ca_topic_score_gemma":0.001367453,"domain_scores_codex":[0.9997923,0.00005091655,0.00002863939,0.00004245531,0.00003212232,0.00005357286],"domain_scores_gemma":[0.9987621,0.0002003458,0.0006503988,0.00008120389,0.00005377793,0.0002521118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003601797,0.00003496262,0.9979711,0.000003312867,0.00001985371,0.00007339527,0.00002164274,0.00002892569,0.000290132,0.000008908731,0.00002848587,0.001159195],"study_design_scores_gemma":[0.00001921105,0.0003773814,0.9985099,0.000006297387,0.00004152734,0.0004389646,0.00007650394,0.0001963981,0.0001840566,0.00003036487,0.0001164824,0.00000266022],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996974,0.00009748105,0.00002454325,0.00001180403,0.000002557051,0.00000196167,0.00006413658,7.166241e-7,0.00009935033],"genre_scores_gemma":[0.9998442,0.00002199854,0.00001282233,0.000007250793,0.000002768058,0.000001061147,0.0000855428,4.451041e-7,0.00002392838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001061709,"threshold_uncertainty_score":0.003500819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02799337944243635,"score_gpt":0.2789281891207626,"score_spread":0.2509348096783262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}