{"id":"W4385724255","doi":"10.1038/s41598-023-29732-4","title":"Development of a spore-based mucosal vaccine against the bovine respiratory pathogen Mannheimia haemolytica","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada","keywords":"Bovine respiratory disease; Microbiology; Pathogen; Nasal administration; Spore; Antigen; Biology; Respiratory tract; Adjuvant; Virology; Immunology; Respiratory system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001256306,0.0002730805,0.0002059224,0.0001162228,0.00005036047,0.0001362961,0.0001384562,0.0003145588,0.0003109524],"category_scores_gemma":[0.00009054568,0.00009136609,0.0002074904,0.00007749975,0.00007428548,0.0001575728,0.0001656079,0.0003616433,0.0001036866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000105149,"about_ca_system_score_gemma":0.0001374907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000209545,"about_ca_topic_score_gemma":0.0003008928,"domain_scores_codex":[0.9999328,0.00001170119,0.000005653572,0.00001380051,0.00002224951,0.00001384841],"domain_scores_gemma":[0.9999605,0.000005862762,0.00001506896,0.000002837389,0.000007083896,0.00000871404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004159848,0.00004942133,0.0002086779,0.00003784187,0.000003369022,0.00001661627,0.000005532006,0.0001451125,0.9971054,0.00002024715,0.00001279306,0.002353397],"study_design_scores_gemma":[0.00008065758,0.006134266,0.01012518,0.00002748746,0.00007098768,0.0004555214,0.00004406918,0.004230446,0.9756183,0.00005096508,0.003155148,0.000007077667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901304,0.001242599,0.007938923,0.00006788957,0.00002015496,0.000075243,0.00008337398,0.0000404686,0.0004009096],"genre_scores_gemma":[0.9812677,0.001458462,0.01595375,0.00006234217,0.00001207343,0.00004898154,0.000456379,0.000007227575,0.0007331685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003145588,"threshold_uncertainty_score":0.00104028,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03106384909698517,"score_gpt":0.2850446054611717,"score_spread":0.2539807563641865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}