{"id":"W4385737795","doi":"10.3390/v15081716","title":"Components of the Nucleotide Salvage Pathway Increase Frog Virus 3 (FV3) Replication","year":2023,"lang":"en","type":"article","venue":"Viruses","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trent University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Inosine; Purine metabolism; Biology; Inosine monophosphate; Adenosine; Purine; Hypoxanthine; Viral replication; Catabolism; Biochemistry; Metabolic pathway; Nucleotide; Adenine nucleotide; Metabolism; Virus; Virology; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001365966,0.000358148,0.0003083016,0.0001484729,0.0001476954,0.0002194502,0.0001441991,0.0003791987,0.001717834],"category_scores_gemma":[0.0001970817,0.0001114471,0.0002303878,0.0001023104,0.0001641905,0.000175729,0.000157014,0.0004426164,0.00023212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002173827,"about_ca_system_score_gemma":0.0001953926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005178375,"about_ca_topic_score_gemma":0.0008601435,"domain_scores_codex":[0.9998758,0.00003932769,0.00001070702,0.00002253735,0.00002684254,0.00002484211],"domain_scores_gemma":[0.9998796,0.00004372513,0.00002800186,0.0000103046,0.00001055982,0.00002774109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001988948,0.00003228164,0.0001270007,0.00004625582,0.000004994828,0.00001847333,0.00001044766,0.00003233685,0.9979109,0.00002804629,0.00001860637,0.001571653],"study_design_scores_gemma":[0.00001455943,0.001385089,0.003663607,0.00001101276,0.00001599452,0.0001060731,0.000021454,0.0002502773,0.9930398,0.00002663747,0.001461881,0.000003637674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992223,0.00397023,0.001471658,0.00009590502,0.00004055162,0.00005643431,0.0003142188,0.00009441571,0.001733712],"genre_scores_gemma":[0.99133,0.00164481,0.004586926,0.00008188621,0.0000210995,0.00004948353,0.0005807995,0.00002125524,0.001683601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001717834,"threshold_uncertainty_score":0.005746722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03988718698521944,"score_gpt":0.3106200104703306,"score_spread":0.2707328234851112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}