{"id":"W4385739018","doi":"10.1101/2023.08.08.552539","title":"Cardiac function and ECM morphology are altered with high fat diets in <i>Drosophila</i>","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"McMaster University","keywords":"Extracellular matrix; Fibrosis; Phenotype; Obesity; Inflammation; Disease; Biology; Cardiac fibrosis; Cardiac function curve; Internal medicine; Drosophila (subgenus); Endocrinology; Medicine; Bioinformatics; Physiology; Cell biology; Heart failure; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001567979,0.0003893382,0.0001896507,0.0004636242,0.0002682439,0.000441798,0.0002866657,0.0005536136,0.002290072],"category_scores_gemma":[0.0001232028,0.0002004125,0.000270811,0.0001748415,0.0005018399,0.0002285993,0.0003735986,0.001120777,0.000508018],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005108916,"about_ca_system_score_gemma":0.0001316402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002111731,"about_ca_topic_score_gemma":0.003429865,"domain_scores_codex":[0.9998345,0.00002218859,0.00001973699,0.00005184303,0.00004197291,0.00002962667],"domain_scores_gemma":[0.9996899,0.00004690387,0.000135494,0.00002126153,0.00002033272,0.00008610232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007968186,0.00002048278,0.0003700326,0.0000240702,0.00000824277,0.00005672545,0.00002505047,0.00006214637,0.9984781,0.0001212931,0.0001042465,0.0006499606],"study_design_scores_gemma":[0.0000357869,0.0002458323,0.04657741,0.00003628262,0.00003742428,0.00059376,0.0002271042,0.002112169,0.9443327,0.0001773009,0.005588663,0.00003562845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888057,0.0008015289,0.003808707,0.0002969526,0.00005593356,0.00002923274,0.003426254,0.0001592911,0.002616467],"genre_scores_gemma":[0.9834607,0.0005637662,0.005009673,0.0003115417,0.00001477909,0.00006951138,0.002020988,0.0002603157,0.008288857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002290072,"threshold_uncertainty_score":0.007661045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01846132559644952,"score_gpt":0.2208847380590848,"score_spread":0.2024234124626353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}