{"id":"W4385740534","doi":"10.3390/pharmaceutics15082114","title":"Non-Invasive Vaccines: Challenges in Formulation and Vaccine Adjuvants","year":2023,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Immunogenicity; Medicine; Commercialization; Risk analysis (engineering); Intensive care medicine; Immunology; Business; Immune system; Marketing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004773023,0.0005043183,0.001476116,0.0005485897,0.0001151295,0.00001749556,0.0002889158,0.0006094463,0.0001099824],"category_scores_gemma":[0.0001148745,0.00042284,0.000203622,0.0003283692,0.00003107878,0.0001223951,0.0001683778,0.0007393076,0.0006806596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000081163,"about_ca_system_score_gemma":0.0001709649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001511301,"about_ca_topic_score_gemma":0.00003507591,"domain_scores_codex":[0.9979208,0.0003315866,0.0007586213,0.0004510609,0.0000387164,0.0004992649],"domain_scores_gemma":[0.9983863,0.0008792997,0.0003213532,0.0003446706,0.0000454026,0.00002297252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001421825,0.00007323278,0.00002353655,0.00865231,0.0005672068,0.00001997364,0.0004746014,5.082279e-7,0.0003575163,0.00005373044,0.0002250918,0.9894101],"study_design_scores_gemma":[0.001884224,0.00008845134,0.0001621559,0.006555774,0.0004521302,0.0001406215,0.0001224685,0.000004116744,0.0005406261,0.00004697133,0.9895614,0.0004410916],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004169624,0.9972402,0.000002108516,0.00007353375,0.001042438,0.0009567715,0.00004539024,0.00009442132,0.0001281603],"genre_scores_gemma":[0.0004600186,0.99779,0.000007338133,0.00004442986,0.00006797243,0.0001289499,0.0002259391,0.00009533824,0.001180048],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9893363,"threshold_uncertainty_score":0.9998223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1747594159580495,"score_gpt":0.4013036875381093,"score_spread":0.2265442715800598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}