{"id":"W4385740534","doi":"10.3390/pharmaceutics15082114","title":"Non-Invasive Vaccines: Challenges in Formulation and Vaccine Adjuvants","year":2023,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Immunogenicity; Medicine; Commercialization; Risk analysis (engineering); Intensive care medicine; Immunology; Business; Immune system; Marketing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001365782,0.0008484813,0.001463412,0.001567892,0.0002851972,0.001558448,0.0009391472,0.001557371,0.002120596],"category_scores_gemma":[0.0009653309,0.0004537038,0.000607671,0.001261688,0.000759461,0.002181059,0.0007762808,0.003187334,0.001833582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006918777,"about_ca_system_score_gemma":0.001131737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007299199,"about_ca_topic_score_gemma":0.0008591589,"domain_scores_codex":[0.9993287,0.0001441486,0.00006453239,0.00008687685,0.0003142592,0.00006138287],"domain_scores_gemma":[0.9993775,0.0003618587,0.00008546464,0.00002200245,0.0001251565,0.00002793271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007014767,0.000166912,0.0001863001,0.02411395,0.0000695398,0.000282059,0.0001362695,0.001034832,0.02449433,0.01862331,0.01413716,0.9166852],"study_design_scores_gemma":[0.00001150676,0.0002540116,0.0004789683,0.002981038,0.0000669332,0.001563463,0.0001054361,0.0003071636,0.00795899,0.004583634,0.9816567,0.0000320611],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004560196,0.9962085,0.001165005,0.0004591596,0.0002932127,0.00001368945,0.00001781077,0.00001399412,0.001372652],"genre_scores_gemma":[0.00208375,0.9951437,0.00116684,0.0003046385,0.0002607958,0.00002325659,0.00003616104,0.000004542863,0.0009763965],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002120596,"threshold_uncertainty_score":0.00722301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1747594159580495,"score_gpt":0.4013036875381093,"score_spread":0.2265442715800598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}