{"id":"W4385757348","doi":"10.1016/j.ijrobp.2023.03.074","title":"Radiation Therapy in the Molecular Era of Lung Cancer: How Best to Integrate Targeted Therapeutics With Definitive Radiation Therapy for Epidermal Growth Factor Receptor–Mutant Unresectable Stage III Non-Small Cell Lung Cancer?","year":2023,"lang":"en","type":"letter","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Osimertinib; Medicine; Epidermal growth factor receptor; Lung cancer; Oncology; Radiation therapy; Targeted therapy; Internal medicine; Cancer research; Cancer; Erlotinib","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001636581,0.0004035754,0.0009443761,0.0004072482,0.002072403,0.001860737,0.0008508656,0.02715066,0.003122574],"category_scores_gemma":[0.01025108,0.0003523335,0.001010962,0.0003854533,0.001522908,0.002745052,0.0009736778,0.02263802,0.002148572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003073818,"about_ca_system_score_gemma":0.003804699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002591741,"about_ca_topic_score_gemma":0.006715158,"domain_scores_codex":[0.9987465,0.0003660952,0.0001671936,0.0001324971,0.0004008113,0.0001870001],"domain_scores_gemma":[0.9969573,0.001608519,0.0002174255,0.00008660392,0.0004208565,0.0007093804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000194928,0.0001563392,0.002753067,0.0001289753,0.00004336418,0.009783044,0.000178607,0.0004920969,0.0008836394,0.007935054,0.9369265,0.04052438],"study_design_scores_gemma":[0.0002932513,0.0002551128,0.002562918,0.0004644452,0.00007290961,0.0161015,0.0004927907,0.001685051,0.0006083547,0.02880662,0.9485623,0.00009473877],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.0008504712,0.001881105,0.0001279344,0.986113,0.009127889,0.000006747828,0.00001885038,0.00001331642,0.001860715],"genre_scores_gemma":[0.01114941,0.003498462,0.0006949466,0.9286347,0.05139665,0.00002727802,0.00003369378,0.00002040951,0.004544526],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.02715066,"threshold_uncertainty_score":0.02230215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02571870403720141,"score_gpt":0.3475316001528025,"score_spread":0.3218128961156012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}