{"id":"W4385758746","doi":"10.3390/polym15163382","title":"Anti-Melanogenesis and Anti-Photoaging Effects of the Sulfated Polysaccharides Isolated from the Brown Seaweed Padina boryana","year":2023,"lang":"en","type":"article","venue":"Polymers","topic":"Seaweed-derived Bioactive Compounds","field":"Agricultural and Biological Sciences","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Natural Science Foundation of Qingdao; Postdoctoral Innovation Project of Shandong Province; Korea Basic Science Institute","keywords":"HaCaT; Photoaging; Reactive oxygen species; Antioxidant; Melanin; Nutraceutical; Polysaccharide; Chemistry; Fucoidan; Cosmeceutical; Dermal fibroblast; Biochemistry; Biology; Fibroblast; In vitro; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009283938,0.0004948523,0.0002602556,0.0004122495,0.0001773011,0.0001811647,0.00007977435,0.0001772394,0.0004669404],"category_scores_gemma":[0.000110405,0.0001505697,0.000357765,0.0002303933,0.0001634457,0.0002193804,0.000259996,0.0004281189,0.00006080231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000108908,"about_ca_system_score_gemma":0.0002236834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007088941,"about_ca_topic_score_gemma":0.0009565012,"domain_scores_codex":[0.9999391,0.00001330999,0.000006863719,0.00001116544,0.00001740194,0.00001208449],"domain_scores_gemma":[0.9999332,0.000009257888,0.00001841075,0.000005954856,0.00001274914,0.00002040092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000193351,0.00005247895,0.0004703189,0.0001410542,0.00001327205,0.00008343314,0.0000236151,0.00006399635,0.9948638,0.00003173785,0.00001977169,0.004043107],"study_design_scores_gemma":[0.0000545206,0.001408452,0.0289763,0.00003903999,0.00008539129,0.000493641,0.0001010429,0.0003857863,0.9654682,0.00006907506,0.002906375,0.00001218028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932451,0.004794847,0.0007445037,0.0000823162,0.0000216361,0.00002423877,0.0001158267,0.00001603846,0.00095555],"genre_scores_gemma":[0.994662,0.002480875,0.001419681,0.00007928955,0.00001245233,0.00001717518,0.0001701412,0.000005568158,0.001152933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007088941,"threshold_uncertainty_score":0.001562059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01317995844045189,"score_gpt":0.2043313574611025,"score_spread":0.1911513990206506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}