{"id":"W4385778709","doi":"10.14814/phy2.15793","title":"Stanniocalcin‐2 inhibits skeletal muscle growth and is upregulated in functional overload‐induced hypertrophy","year":2023,"lang":"en","type":"article","venue":"Physiological Reports","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; FP7 People: Marie-Curie Actions; National Institutes of Health; Danmarks Frie Forskningsfond; Michael Smith Health Research BC; UK Research and Innovation; Chief Scientist Office; St. Paul's Foundation; Wellcome Trust","keywords":"Muscle hypertrophy; Downregulation and upregulation; Endocrinology; Plantaris muscle; Internal medicine; Skeletal muscle; Myokine; Growth factor; Myocyte; Biology; Matrix metalloproteinase; Chemistry; Medicine; Receptor; Soleus muscle; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001850254,0.0006606316,0.0004546673,0.0004521481,0.0001742294,0.0003134966,0.0002308219,0.0003607376,0.00187422],"category_scores_gemma":[0.0001554806,0.0001871812,0.0002628859,0.0002097207,0.0005140258,0.0002429985,0.0002550521,0.0006704812,0.000225706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004126431,"about_ca_system_score_gemma":0.000307609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007111396,"about_ca_topic_score_gemma":0.00124484,"domain_scores_codex":[0.9997789,0.00002381736,0.00001303448,0.00003657514,0.00008045385,0.0000672346],"domain_scores_gemma":[0.9997032,0.00002130513,0.00007649252,0.00001618719,0.00003539437,0.0001473705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005843726,0.00005462878,0.0003046344,0.00004429034,0.00000858366,0.00002867131,0.000006305211,0.00002543594,0.9983375,0.00001599791,0.00002662983,0.0005630284],"study_design_scores_gemma":[0.000103117,0.001634569,0.01806813,0.00000951424,0.00003812579,0.0002653195,0.00005186547,0.0006613648,0.9780564,0.00003049142,0.001075115,0.000006054531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965039,0.001444836,0.0008121802,0.00009033329,0.00004242146,0.00002150844,0.0001930095,0.0001102886,0.0007813745],"genre_scores_gemma":[0.9955687,0.0005480504,0.0008232321,0.00006993685,0.00002175273,0.00005142068,0.0004545491,0.00003482587,0.002427504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00187422,"threshold_uncertainty_score":0.006269872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03292931521185292,"score_gpt":0.2357698377623804,"score_spread":0.2028405225505275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}