{"id":"W4385802331","doi":"10.3390/organoids2030011","title":"Incorporating Immune Cells into Organoid Models: Essential for Studying Human Disease","year":2023,"lang":"en","type":"article","venue":"Organoids","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Organoid; Biology; Disease; Human disease; Function (biology); Immunology; Cell biology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002657384,0.0008054441,0.0008295161,0.001022366,0.0005995316,0.001477172,0.00101592,0.001484103,0.003188469],"category_scores_gemma":[0.001475377,0.0005375842,0.0006711668,0.000598818,0.001163495,0.001906618,0.001182588,0.002974893,0.001628352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008225788,"about_ca_system_score_gemma":0.000872627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001155904,"about_ca_topic_score_gemma":0.001770741,"domain_scores_codex":[0.9988813,0.0004676318,0.00007937729,0.0001436472,0.0003385719,0.00008944712],"domain_scores_gemma":[0.9987673,0.0003129488,0.0001884008,0.0003756883,0.000186157,0.0001695571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005528491,0.0003318319,0.00150662,0.0009866072,0.00006390006,0.0007173573,0.0004617556,0.00269723,0.9473332,0.01019223,0.003545047,0.03161145],"study_design_scores_gemma":[0.0001889808,0.00166747,0.003837038,0.001184099,0.0002392531,0.003302623,0.0007608708,0.009696844,0.7603012,0.008098196,0.2106078,0.0001155539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1669115,0.05375617,0.741658,0.007379426,0.002642902,0.001775659,0.004351558,0.002702134,0.01882252],"genre_scores_gemma":[0.6013061,0.03890534,0.3394225,0.001693614,0.0002438935,0.003153262,0.003760312,0.0008072029,0.01070774],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003188469,"threshold_uncertainty_score":0.01405376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02528746185527625,"score_gpt":0.2555558089989663,"score_spread":0.23026834714369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}