{"id":"W4385812380","doi":"10.3390/brainsci13081195","title":"Associations between Neuropsychiatric Symptoms and Alzheimer’s Disease Biomarkers in People with Mild Cognitive Impairment","year":2023,"lang":"en","type":"article","venue":"Brain Sciences","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; Foundation for the National Institutes of Health","keywords":"Biomarker; Internal medicine; Atrophy; Cognitive impairment; Medicine; Oncology; Disease; Alzheimer's disease; Alzheimer's Disease Neuroimaging Initiative; Cognitive decline; Cerebrospinal fluid; Dementia; Psychology; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009556415,0.0001157149,0.0001768842,0.0005555019,0.000241273,0.0000767699,0.00009231924,0.00002375154,0.00004063004],"category_scores_gemma":[0.000223394,0.00008578493,0.00003752908,0.002723489,0.0003249831,0.0001541914,0.00007664767,0.00009425353,0.00003944561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002528124,"about_ca_system_score_gemma":0.0003088452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001191584,"about_ca_topic_score_gemma":0.00008239481,"domain_scores_codex":[0.9982142,0.0001225799,0.0001742109,0.0003996193,0.0006661567,0.000423247],"domain_scores_gemma":[0.9990172,0.0005162288,0.00005551569,0.00007681116,0.00007101353,0.0002632284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007008421,0.00009290953,0.9949229,0.00001053735,0.00008553522,0.00002964184,0.0002403258,7.570935e-7,0.00001134434,0.00002768811,0.0007918018,0.003716415],"study_design_scores_gemma":[0.001563938,0.0007576856,0.9961537,0.00008044996,0.0001356869,0.000002517967,0.0007659117,0.0002458582,0.0000209516,0.0001215973,0.00004289282,0.0001088512],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987284,0.0002230666,0.00001285041,0.01014898,0.00003757828,0.0007816358,0.00007296642,0.00006102624,0.001377868],"genre_scores_gemma":[0.9990362,0.00004657731,0.000043052,0.0005027473,0.00004527201,0.00006354033,0.00006590893,0.000008871825,0.0001878177],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01175218,"threshold_uncertainty_score":0.3498208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03545300173197361,"score_gpt":0.3474689848360687,"score_spread":0.3120159831040951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}