{"id":"W4385814583","doi":"10.53879/id.60.07.p0005","title":"IT IS TIME TO TAKE ADVANTAGE OF IN VITRO CELL BASED MODELS","year":2023,"lang":"en","type":"article","venue":"INDIAN DRUGS","topic":"Animal testing and alternatives","field":"Veterinary","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Animal testing; Government (linguistics); Clinical trial; Animal welfare; European union; Animal model; Human studies; Immunogenicity; Medicine; Experimental animal; Risk analysis (engineering); Biotechnology; Pharmacology; Public economics; Business; Veterinary medicine; Biology; Pathology; International trade; Economics; Immunology; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001755893,0.000108556,0.000166746,0.0002364001,0.00002639728,0.00001111709,0.0001947532,0.00004009275,0.0003991068],"category_scores_gemma":[0.00002887204,0.0001118044,0.00005357221,0.0003545527,0.00002403209,0.00008162856,0.00006516817,0.0001010354,0.002755735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002609737,"about_ca_system_score_gemma":0.00003548572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006658885,"about_ca_topic_score_gemma":0.000001387259,"domain_scores_codex":[0.9991354,0.00004135806,0.0001954423,0.0002233452,0.0001602618,0.0002442126],"domain_scores_gemma":[0.9995053,0.0001499493,0.00005947688,0.0001878343,0.00002132652,0.0000761112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001520766,0.0004764656,0.002272218,0.0004289169,0.0000396193,0.002125647,0.06862264,0.002992032,0.8609695,0.0000245875,0.04482488,0.01570268],"study_design_scores_gemma":[0.005381767,0.00331438,0.01077046,0.001277194,0.00004136295,0.00003359212,0.01067214,0.316634,0.6151843,0.00299677,0.03145836,0.002235691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9663656,0.00001070356,0.00003447495,0.0008392757,0.00002753664,0.0001317991,0.0001663782,0.00009935739,0.03232487],"genre_scores_gemma":[0.9925508,0.000001186993,0.0008368242,0.0009826632,0.00003473129,0.0000127453,0.0000164127,0.00002577631,0.005538879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.313642,"threshold_uncertainty_score":0.9980207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07909140736009,"score_gpt":0.349774390875511,"score_spread":0.270682983515421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}