{"id":"W4385836735","doi":"10.2196/preprints.51783","title":"A Hospital-Wide Open-Label Cluster Crossover Pragmatic Comparative Effectiveness Randomized Trial Comparing Normal Saline to Ringer’s Lactate: Protocol and Statistical Analysis Plan of The FLUID Trial (Preprint)","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Renal function and acid-base balance","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Randomized controlled trial; Dialysis; Emergency medicine; Crossover study; Renal replacement therapy; Cluster (spacecraft); Placebo; Intensive care medicine; Surgery","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04727571,0.006180094,0.008439236,0.002626662,0.002457594,0.005577515,0.002944111,0.005443969,0.05619026],"category_scores_gemma":[0.05648741,0.003266598,0.006494269,0.003555409,0.003783971,0.002795761,0.00193465,0.006529845,0.009550991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005812066,"about_ca_system_score_gemma":0.02197929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004450652,"about_ca_topic_score_gemma":0.005844722,"domain_scores_codex":[0.9692239,0.02245421,0.002130707,0.002024183,0.002573554,0.001593424],"domain_scores_gemma":[0.9818382,0.006519413,0.003148026,0.002369346,0.003882536,0.002242337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8402705,0.01082652,0.001988618,0.03073819,0.005529165,0.0004667191,0.000623416,0.005669332,0.001796296,0.01333966,0.05121136,0.03754029],"study_design_scores_gemma":[0.9180336,0.02131684,0.00243451,0.004697349,0.002290416,0.000107186,0.000211587,0.004854346,0.0009428485,0.005894363,0.03904467,0.0001723146],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.001763747,0.0002215427,0.001570879,0.0003420457,0.0004191617,0.9931324,0.001651011,0.00006787212,0.000831424],"genre_scores_gemma":[0.001926865,0.0001000156,0.002805806,0.0002792582,0.00005802392,0.9942173,0.0002839926,0.000006094007,0.0003225684],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.05619026,"threshold_uncertainty_score":0.2500208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06533253668715544,"score_gpt":0.3937627558624343,"score_spread":0.3284302191752789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}