{"id":"W4385858569","doi":"10.1016/j.bja.2023.05.030","title":"Depth of sedation with dexmedetomidine increases transcranial magnetic stimulation-evoked potential amplitude non-linearly","year":2023,"lang":"en","type":"article","venue":"British Journal of Anaesthesia","topic":"Transcranial Magnetic Stimulation Studies","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centres Intégré Universitaires de Santé et de Services Sociaux","funders":"Erasmus+; HORIZON EUROPE Framework Programme; Koning Boudewijnstichting; Fundação Bial; Université de Liège; Fondation Université Européenne du Travail; James S. McDonnell Foundation; AstraZeneca Foundation; Fonds De La Recherche Scientifique - FNRS; Mind Science Foundation; Fondazione Europea Ricerca Biomedica; Belgian Federal Science Policy Office","keywords":"Dexmedetomidine; Sedation; Transcranial magnetic stimulation; Anesthesia; Unconsciousness; Posterior parietal cortex; Medicine; Evoked potential; Wakefulness; Cortex (anatomy); Electroencephalography; Stimulation; Neuroscience; Psychology; Internal medicine; Audiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003496515,0.0001951355,0.00046769,0.0003322521,0.0001838326,0.0001058176,0.0002951777,0.00007465424,0.0001122963],"category_scores_gemma":[0.0003871871,0.0001996036,0.000168641,0.0009215847,0.0002451968,0.0003659094,0.00001711473,0.0002010119,0.00001585767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002522509,"about_ca_system_score_gemma":0.0001339182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003270672,"about_ca_topic_score_gemma":0.0001460353,"domain_scores_codex":[0.9976089,0.0001700394,0.0007963417,0.0002682613,0.0008542102,0.0003022577],"domain_scores_gemma":[0.998663,0.0002703678,0.0004161789,0.0001442015,0.0003627106,0.0001435433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004480702,0.001264195,0.03100329,0.0002283817,0.0001268818,0.004949309,0.001432906,0.09420198,0.7044408,0.0002619047,0.0008217077,0.1567879],"study_design_scores_gemma":[0.003862318,0.002492269,0.9795253,0.0003588426,0.000211327,0.001626865,0.0001326723,0.00703618,0.004081591,0.0002692093,0.0001081411,0.0002952795],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943937,0.0002256354,0.004483111,0.0002727485,0.0001091328,0.0002981713,0.00002918095,0.00005890692,0.0001293865],"genre_scores_gemma":[0.9973799,0.0005500587,0.001713561,0.00008189122,0.0001673332,0.000005523909,0.000004626784,0.0000393537,0.00005772882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.948522,"threshold_uncertainty_score":0.81396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.020326240392622,"score_gpt":0.2530817956450671,"score_spread":0.2327555552524451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}