{"id":"W4385896190","doi":"10.22541/au.169175892.29540325/v1","title":"Therapeutic-like activity of cannabidiolic acid methyl ester (HU-580) in the MK-801 mouse model of schizophrenia: role for cannabinoid CB1 and serotonin-1A receptors","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Serotonergic; Schizophrenia (object-oriented programming); Endocannabinoid system; Cannabinoid; Antipsychotic; Cannabinoid receptor; Serotonin; Psychology; Psychosis; Receptor; Pharmacology; Neuroscience; Medicine; Internal medicine; Psychiatry; Agonist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002404053,0.0009564711,0.0006011855,0.0008947248,0.0002818706,0.0002879672,0.0003919181,0.0006399638,0.001877344],"category_scores_gemma":[0.0001003871,0.0003575328,0.0005476375,0.0002594861,0.0005360756,0.0003842381,0.0002308511,0.001463971,0.0004575102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005125634,"about_ca_system_score_gemma":0.0004963265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001740313,"about_ca_topic_score_gemma":0.002968014,"domain_scores_codex":[0.9997814,0.00002748405,0.00002331945,0.00003956563,0.00004910563,0.00007911372],"domain_scores_gemma":[0.9998009,0.00001027614,0.00005357864,0.00001375902,0.00001350064,0.0001079797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008899971,0.0004317207,0.0002538257,0.00005592143,0.00001219896,0.0001451742,0.00003479049,0.00007728065,0.996859,0.0001277191,0.00006778124,0.00104461],"study_design_scores_gemma":[0.0002008935,0.00710617,0.007988577,0.00002435976,0.00006016284,0.0004870131,0.00008872247,0.001389009,0.9811623,0.0001288069,0.001343761,0.00002021189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957847,0.0007269363,0.001128916,0.0002325288,0.0000552904,0.0000678939,0.0007117871,0.0001328343,0.001159031],"genre_scores_gemma":[0.9902939,0.001159365,0.001924212,0.0001094141,0.00001901569,0.0001501995,0.0006826546,0.00002639216,0.00563496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001877344,"threshold_uncertainty_score":0.006280303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05394163165403005,"score_gpt":0.3301055097004189,"score_spread":0.2761638780463888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}