{"id":"W4385945346","doi":"10.1021/jasms.3c00134","title":"All-in-One Pseudo-MS<sup>3</sup> Method for the Analysis of Gas-Phase Cleavable Protein Crosslinking Reactions","year":2023,"lang":"en","type":"article","venue":"Journal of the American Society for Mass Spectrometry","topic":"Mass Spectrometry Techniques and Applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; National Cancer Institute; Canarie","keywords":"Chemistry; Peptide; Mass spectrometry; Gas phase; Fragmentation (computing); Combinatorial chemistry; Chromatography; Proteomics; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00105802,0.001957543,0.000512636,0.00112058,0.0006656522,0.0008262707,0.001677549,0.001147607,0.010257],"category_scores_gemma":[0.001624357,0.0007718991,0.0006521859,0.0005725551,0.0007824147,0.001017433,0.0009374985,0.00208256,0.005098974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005360012,"about_ca_system_score_gemma":0.0009639141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000295639,"about_ca_topic_score_gemma":0.0008829467,"domain_scores_codex":[0.9989268,0.0001961661,0.00006786513,0.0001697557,0.0005828808,0.00005647753],"domain_scores_gemma":[0.9985244,0.0004563277,0.0003158057,0.0002710847,0.0003392485,0.00009323633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000320903,0.00004749701,0.0008713485,0.0003270606,0.00005091989,0.0003330907,0.00005261052,0.0004580381,0.9621419,0.001712755,0.002923958,0.03075993],"study_design_scores_gemma":[0.00001824607,0.0001530434,0.001462774,0.00002523446,0.00003485265,0.001329616,0.00003179004,0.008614926,0.9608987,0.001022612,0.02636727,0.00004096757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.06018013,0.003756924,0.914643,0.0007082592,0.0006294542,0.0006515994,0.002609645,0.009180572,0.007640386],"genre_scores_gemma":[0.1549925,0.003203792,0.8120433,0.0015689,0.0001476591,0.001595949,0.004620614,0.003076534,0.01875076],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.010257,"threshold_uncertainty_score":0.03431308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0361634824145847,"score_gpt":0.3548346063084062,"score_spread":0.3186711238938215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}