{"id":"W4385955146","doi":"10.3390/cancers15164148","title":"Unraveling the Role of EV-Derived miR-150-5p in Prostate Cancer Metastasis and Its Association with High-Grade Gleason Scores: Implications for Diagnosis","year":2023,"lang":"en","type":"article","venue":"Cancers","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Universidad Nacional Autónoma de México; Consejo Nacional de Ciencia y Tecnología","keywords":"Prostate cancer; Metastasis; Medicine; microRNA; Lymph; Prostate; Lymph node; Cancer; Microvesicles; Cancer research; Pathology; Oncology; Wnt signaling pathway; Internal medicine; Biology; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003340572,0.0003374773,0.0003594968,0.0005529578,0.0001261149,0.0006033381,0.000214507,0.0003495485,0.0006167379],"category_scores_gemma":[0.0005276456,0.0001862025,0.0003315074,0.0003411544,0.0002213404,0.0003379772,0.0002491484,0.0004000359,0.000199476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000243987,"about_ca_system_score_gemma":0.0003228862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004957015,"about_ca_topic_score_gemma":0.0005011399,"domain_scores_codex":[0.999838,0.00003866374,0.00001646367,0.00004027093,0.00004197622,0.00002470019],"domain_scores_gemma":[0.9997864,0.00005174431,0.00008704785,0.00001278382,0.00003517555,0.00002688418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008585086,0.0001295392,0.1343756,0.0008059114,0.0002572595,0.001246101,0.0002011534,0.0009683997,0.7954692,0.001700596,0.0009228644,0.06306498],"study_design_scores_gemma":[0.00004926763,0.001040455,0.6110523,0.0002665947,0.0006281484,0.01072419,0.0005964696,0.01626192,0.333612,0.003548716,0.0221201,0.00009986399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9441448,0.04388829,0.008982017,0.0006078333,0.00007390251,0.00003447228,0.0005615673,0.0001151084,0.00159192],"genre_scores_gemma":[0.9901128,0.005579942,0.003291107,0.000176445,0.00003913221,0.00001713621,0.0002928337,0.00001509037,0.0004755106],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006167379,"threshold_uncertainty_score":0.002063155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01376634614743455,"score_gpt":0.2754126761578911,"score_spread":0.2616463300104565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}