{"id":"W4385955561","doi":"10.1097/01.hs9.0000972472.24418.bc","title":"P1396: CD33-DELETED HEMATOPOIETIC STEM AND PROGENITOR CELLS DISPLAY NORMAL ENGRAFTMENT AFTER HEMATOPOIETIC CELL TRANSPLANT (HCT) AND TOLERATE POST-HCT GEMTUZUMAB OZOGAMICIN (GO) WITHOUT CYTOPENIAS","year":2023,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Gemtuzumab ozogamicin; Medicine; CD33; Plerixafor; Fludarabine; CD34; Myeloid; Hematopoietic stem cell transplantation; Stem cell; Melphalan; Busulfan; Haematopoiesis; Internal medicine; Immunology; Transplantation; Oncology; Chemotherapy; Immune system; CXCR4; Cyclophosphamide; Biology; Chemokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004431498,0.0007001029,0.001033751,0.0001953334,0.0002235594,0.0002304657,0.0002014441,0.0003210196,0.001816229],"category_scores_gemma":[0.00001186129,0.0005831267,0.0002269366,0.0005408836,0.0002673021,0.0002624519,0.0001992373,0.0006428641,0.000438489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001751924,"about_ca_system_score_gemma":0.0002274966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001061946,"about_ca_topic_score_gemma":0.000110234,"domain_scores_codex":[0.9958687,0.0002023397,0.0007365683,0.001046021,0.0009653082,0.001181027],"domain_scores_gemma":[0.9979174,0.0002459645,0.000137086,0.0007865339,0.0002045042,0.000708561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006466295,0.0007534248,0.03786279,0.005896149,0.0005626433,0.005125505,0.01455276,0.00002740888,0.9216657,0.00007486944,0.001688409,0.005324102],"study_design_scores_gemma":[0.01825338,0.003612507,0.02522117,0.002216236,0.001059873,0.003399585,0.005888542,0.003332983,0.9200134,0.00005120637,0.01469441,0.002256735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935591,0.001822019,0.00004185129,0.0005872637,0.0001878825,0.002620712,0.0001397302,0.0002971518,0.0007443072],"genre_scores_gemma":[0.969309,0.0007187258,0.000345411,0.0003358212,0.0001724899,0.0003693782,0.00009642667,0.0001917208,0.02846102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02771671,"threshold_uncertainty_score":0.999662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01368458727992966,"score_gpt":0.2551828161038957,"score_spread":0.241498228823966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}