{"id":"W4385968483","doi":"10.1089/thy.2022.0410","title":"The Origin of Antithyroid Drugs","year":2023,"lang":"en","type":"article","venue":"Thyroid","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Antithyroid drugs; Medicine; Propylthiouracil; Antithyroid agent; Thiouracil; Thyroid; Drug; Graves' disease; Pharmacology; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003453652,0.0001266335,0.0002400005,0.0001207103,0.0001349784,0.0000130728,0.0001673831,0.00006880946,0.00003434615],"category_scores_gemma":[0.000121718,0.00007929053,0.0001237165,0.000713705,0.0001432006,0.0000614308,0.00006325276,0.000179086,0.0007511836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002251464,"about_ca_system_score_gemma":0.00008837439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005227839,"about_ca_topic_score_gemma":0.00000245056,"domain_scores_codex":[0.998819,0.00002876845,0.0003009913,0.0001702744,0.0003485174,0.0003324795],"domain_scores_gemma":[0.9991293,0.0001514312,0.00008141233,0.0004374859,0.00009234115,0.000108008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007137834,0.0002253924,0.05233984,0.000177205,0.0003252872,0.0001070639,0.003331558,0.000005477121,0.4122737,0.01319557,0.4951704,0.02213469],"study_design_scores_gemma":[0.004029517,0.001419134,0.3783673,0.0001027364,0.0002020606,0.00004944417,0.002445123,0.0005424164,0.1733739,0.002800743,0.4361968,0.0004708466],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9711199,0.001003333,0.000009755879,0.00180464,0.0002766485,0.0002193583,0.000008703444,0.0001837322,0.02537396],"genre_scores_gemma":[0.9921144,0.001079613,0.00006024965,0.000206478,0.0001659633,0.00001059034,0.00002271901,0.0000262935,0.006313753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3260275,"threshold_uncertainty_score":0.9655196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02015560880911899,"score_gpt":0.2798453536500664,"score_spread":0.2596897448409474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}