{"id":"W4385973717","doi":"10.1016/j.ophtha.2023.08.011","title":"Study of Late-Onset Stargardt Type 1 Disease","year":2023,"lang":"en","type":"article","venue":"Ophthalmology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Radboud Universitair Medisch Centrum; Health Research Charities Ireland; Health Research Board; Foundation Fighting Blindness","keywords":"Stargardt disease; Medicine; Visual acuity; Atrophy; Ophthalmology; Age of onset; ABCA4; Cohort; Fundus (uterus); Macular degeneration; Pathology; Disease; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001019275,0.0000871013,0.0001090472,0.00005521554,0.00003422691,0.000003422302,0.0001320532,0.00005723929,0.0001088274],"category_scores_gemma":[0.00009034964,0.00008206171,0.00003234871,0.0001806875,0.0000447382,0.000001193764,0.0001197164,0.00003477647,0.00009336399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002586771,"about_ca_system_score_gemma":0.00006007839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001589043,"about_ca_topic_score_gemma":0.000002848856,"domain_scores_codex":[0.9993429,0.00005955719,0.0001344273,0.0002148876,0.00007961541,0.0001685744],"domain_scores_gemma":[0.9996133,0.00001085414,0.0000407908,0.000223017,0.00005107423,0.00006093406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004688515,0.0002535959,0.9833618,0.00001689171,0.00006859416,0.0002679424,0.0001375887,0.00009789924,0.009336486,0.00001312857,0.005856526,0.00012065],"study_design_scores_gemma":[0.000651205,0.001117761,0.9933361,0.000003491824,0.00001857877,0.00003512848,0.0004746424,0.0000104148,0.001657815,0.0003012629,0.002234258,0.0001593663],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966629,0.00009679273,0.00000108742,0.00006228482,0.000182873,0.0001528103,0.000007867143,0.00001188206,0.002821527],"genre_scores_gemma":[0.9957277,0.00003432859,0.00002435724,0.00002442071,0.00002270252,0.00001409737,0.0001801316,0.00001272181,0.00395953],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009974231,"threshold_uncertainty_score":0.3346379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02680532811944768,"score_gpt":0.3052801977835526,"score_spread":0.278474869664105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}