{"id":"W4385978096","doi":"10.3390/metabo13080953","title":"The Native Microbiome Member Chryseobacterium sp. CHNTR56 MYb120 Induces Trehalose Production via a Shift in Central Carbon Metabolism during Early Life in C. elegans","year":2023,"lang":"en","type":"article","venue":"Metabolites","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biology; Glyoxylate cycle; Microbiome; Caenorhabditis elegans; Metabolomics; Dysbiosis; Metabolic pathway; Downregulation and upregulation; Microbiology; Metabolism; Biochemistry; Gene; Genetics; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001197309,0.000285239,0.0001771761,0.0001901481,0.0001553811,0.0001684124,0.0001834383,0.0002603222,0.0009279595],"category_scores_gemma":[0.0001058171,0.0001207894,0.0002367718,0.000109418,0.0001716372,0.0001830974,0.0002653596,0.0004920653,0.0001763458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002655638,"about_ca_system_score_gemma":0.000217509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001422913,"about_ca_topic_score_gemma":0.002342819,"domain_scores_codex":[0.9998888,0.000009246818,0.000008690774,0.00003491347,0.00003475663,0.00002349254],"domain_scores_gemma":[0.9998883,0.00001204991,0.00004027353,0.00001057638,0.00001807904,0.00003067969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005835105,0.00001063809,0.0001993676,0.00002105375,0.000001727428,0.00001422854,0.000005453493,0.00001570815,0.9993182,0.000011567,0.00001461324,0.0003289227],"study_design_scores_gemma":[0.00001160657,0.0004574087,0.02450725,0.00001294515,0.00001596021,0.0001468481,0.00006103126,0.0007831835,0.9723014,0.00004313437,0.001649662,0.000009599454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957055,0.0005624327,0.001655857,0.0001027651,0.0000257092,0.0000301862,0.0009486397,0.00008092942,0.0008879831],"genre_scores_gemma":[0.9945278,0.0004033657,0.002042304,0.00006953344,0.000005167279,0.00005406827,0.0007587405,0.0000210304,0.002117973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001422913,"threshold_uncertainty_score":0.003104329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009182079958732875,"score_gpt":0.2233812000783686,"score_spread":0.2141991201196357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}