{"id":"W4385993062","doi":"10.1016/j.jvs.2023.06.092","title":"Report From A Phase 2 Prospective Randomized Placebo Controlled Trial of Autologous Stem Cells to Treat Patients With No Option Critical Limb Ischemia: The ACP-CLI Trial","year":2023,"lang":"en","type":"article","venue":"Journal of Vascular Surgery","topic":"Peripheral Artery Disease Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Placebo; Critical limb ischemia; Randomized controlled trial; Surgery; Clinical endpoint; Clinical trial; Placebo-controlled study; Revascularization; Amputation; Internal medicine; Anesthesia; Double blind; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004740425,0.002840853,0.004866376,0.0004099221,0.0005530774,0.002315323,0.0009777541,0.003532722,0.01083051],"category_scores_gemma":[0.00639342,0.0006168304,0.004166517,0.0004903213,0.001076674,0.001866527,0.0004498169,0.005727984,0.002120602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006141174,"about_ca_system_score_gemma":0.001055952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009442425,"about_ca_topic_score_gemma":0.001529679,"domain_scores_codex":[0.998336,0.0008962899,0.0001327953,0.0003026244,0.0001697465,0.0001625449],"domain_scores_gemma":[0.9965584,0.00186725,0.0005321243,0.0002495703,0.000320914,0.000471785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9588068,0.001697795,0.0009119661,0.002322239,0.008446161,0.0001418991,0.00006271585,0.0003145107,0.002359769,0.0004078444,0.006997947,0.01753022],"study_design_scores_gemma":[0.9730412,0.01527673,0.002087132,0.000145247,0.005301697,0.00007353035,0.00003129627,0.0001735245,0.0004209547,0.000532216,0.002884619,0.00003183851],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7476726,0.1317011,0.01013073,0.02839021,0.01542585,0.01502444,0.02543494,0.0008497003,0.02537067],"genre_scores_gemma":[0.8951783,0.03047637,0.005917856,0.02729443,0.005989469,0.008379224,0.01306163,0.000175845,0.01352691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01083051,"threshold_uncertainty_score":0.0362317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01416083435558708,"score_gpt":0.2820677159376214,"score_spread":0.2679068815820344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}