{"id":"W4385996382","doi":"10.3410/f.742679729.793600444","title":"Faculty Opinions recommendation of KontRASt-02: A phase III trial investigating the efficacy and safety of the KRAS[G12C] inhibitor JDQ443 vs docetaxel in patients with previously treated, locally advanced or metastatic, KRAS G12C-mutated NSCLC.","year":2023,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Docetaxel; KRAS; Oncology; Medicine; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003172315,0.001218508,0.001927012,0.001271385,0.0006712097,0.002686424,0.002771017,0.002255698,0.1212481],"category_scores_gemma":[0.02210693,0.0006206157,0.002983371,0.002959505,0.0003033139,0.001153855,0.001132241,0.001932131,0.04364578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001775635,"about_ca_system_score_gemma":0.006155593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01310223,"about_ca_topic_score_gemma":0.04692771,"domain_scores_codex":[0.9979275,0.0007248395,0.000325901,0.0003719733,0.0004818485,0.0001678425],"domain_scores_gemma":[0.9918603,0.002598784,0.001750422,0.001205046,0.001622606,0.0009628637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.001484126,0.00005686649,0.00186778,0.002558804,0.000574849,0.0000215254,0.00001005805,0.000211728,0.0001605314,0.0002693315,0.9852609,0.007523546],"study_design_scores_gemma":[0.02192726,0.0002616428,0.0139685,0.00259787,0.001980801,0.0001349131,0.00003540204,0.0009450237,0.0007587141,0.001825647,0.9554963,0.00006795128],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0004105661,0.0003266562,0.000104104,0.0006387722,0.00007785441,0.0001544054,0.9952122,0.0001499825,0.002925567],"genre_scores_gemma":[0.003752954,0.0006039693,0.001005255,0.001353561,0.0001181861,0.0009941672,0.9864449,0.0001815516,0.005545442],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.1212481,"threshold_uncertainty_score":0.4056154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03119623326540499,"score_gpt":0.3585645571182185,"score_spread":0.3273683238528135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}