{"id":"W4385998441","doi":"10.1111/febs.16931","title":"Metabolic characterisation of transglutaminase 2 inhibitor effects in breast cancer cell lines","year":2023,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Blood properties and coagulation","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Tissue transglutaminase; Phosphocholine; Cancer cell; Cell culture; Intracellular; Metabolomics; Biochemistry; Phospholipase; Cell; Biology; Apoptosis; Enzyme; Cancer; Cell biology; Chemistry; Cancer research; Phospholipid; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001180406,0.0002967414,0.0003058329,0.0002823618,0.0001495793,0.0001708316,0.0001351815,0.0002354654,0.0009505955],"category_scores_gemma":[0.0001072357,0.0000974057,0.0002530198,0.0003871145,0.00008487893,0.0001122346,0.0001061062,0.0003649675,0.0003353639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001832069,"about_ca_system_score_gemma":0.0001555903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002236232,"about_ca_topic_score_gemma":0.002658009,"domain_scores_codex":[0.9998939,0.00001688666,0.00001056638,0.00002032764,0.00003888564,0.00001938913],"domain_scores_gemma":[0.9999322,0.0000109785,0.00001028178,0.000008539338,0.00002830062,0.000009795236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001234674,0.00001536638,0.0001404598,0.00002274309,0.000006047011,0.00002957629,0.00001218571,0.00006614388,0.9986896,0.00001570853,0.00003350612,0.0008451327],"study_design_scores_gemma":[0.00000984085,0.0002425348,0.00439368,0.00000335251,0.00002447044,0.000127048,0.00003646357,0.0006890349,0.9926178,0.00002170651,0.001828724,0.000005254879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9781181,0.004574653,0.009411767,0.0002156158,0.00006449249,0.0001055638,0.004092393,0.0001729085,0.003244481],"genre_scores_gemma":[0.9651145,0.004166007,0.01576533,0.0002059556,0.00002274027,0.0002944321,0.007742571,0.00005618884,0.006632235],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002236232,"threshold_uncertainty_score":0.004446447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01421202755336102,"score_gpt":0.2573811821762915,"score_spread":0.2431691546229305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}