{"id":"W4386000748","doi":"10.1101/2023.08.18.553508","title":"CD56-mediated activation of human natural killer cells is triggered by <i>Aspergillus fumigatus</i> galactosaminogalactan","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; SickKids Foundation; McGill University; Hospital for Sick Children; Institute of Infection and Immunity; McGill University Health Centre","funders":"University of Crete; Deutsche Forschungsgemeinschaft","keywords":"Aspergillus fumigatus; Degranulation; Effector; Immune system; Chemokine; Biology; Cytotoxic T cell; Microbiology; Natural killer T cell; Aspergillosis; Natural killer cell; Immunology; Cell biology; T cell; Receptor; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008759651,0.0003606174,0.0001589365,0.0001002019,0.0001244181,0.0002825134,0.00007846745,0.0001647873,0.003577571],"category_scores_gemma":[0.0001194051,0.0000739547,0.0002316254,0.00008360416,0.0001230185,0.00008959669,0.0002409648,0.0002904354,0.0009197438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002015721,"about_ca_system_score_gemma":0.0001258822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004150253,"about_ca_topic_score_gemma":0.0003777278,"domain_scores_codex":[0.9998807,0.000020052,0.00001142836,0.00002416879,0.00002208806,0.00004155049],"domain_scores_gemma":[0.9999682,0.000007181069,0.000005499199,0.000005844278,0.000004480489,0.000008830761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002401136,0.00001450133,0.0006017575,0.00004343814,0.000005034088,0.0001641278,0.00001516952,0.00003200745,0.9969907,0.00008481586,0.0001029445,0.001705406],"study_design_scores_gemma":[0.000053845,0.0001932897,0.01909093,0.00001388343,0.00002020929,0.001065585,0.00005659549,0.0008780026,0.9729803,0.0001120389,0.005530308,0.000005086828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918194,0.001623019,0.001676522,0.0001058811,0.00009058555,0.00004157981,0.0004314129,0.00006443011,0.004147339],"genre_scores_gemma":[0.9956608,0.0004606297,0.0008549522,0.00004854138,0.00001740771,0.00002189516,0.0005872208,0.000006608439,0.002341813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003577571,"threshold_uncertainty_score":0.01196814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01278781542274794,"score_gpt":0.2161233228174165,"score_spread":0.2033355073946685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}