{"id":"W4386022746","doi":"10.1021/acssuschemeng.3c02813","title":"Green and Sustainable Solvents for Solid-Phase Peptoid Synthesis","year":2023,"lang":"en","type":"article","venue":"ACS Sustainable Chemistry & Engineering","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canada First Research Excellence Fund; Natural Sciences and Engineering Research Council of Canada; Mitacs; University of Toronto; Canada Foundation for Innovation","keywords":"Peptoid; Chemistry; Solvent; Green chemistry; Combinatorial chemistry; Hazardous waste; Solid-phase synthesis; Yield (engineering); Solid phase extraction; Organic chemistry; Materials science; Extraction (chemistry); Waste management; Ionic liquid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004891108,0.0008413815,0.0003995746,0.0004783153,0.000346824,0.0005360152,0.0002628193,0.0005682256,0.001142596],"category_scores_gemma":[0.0005903508,0.0002844417,0.000305637,0.0004278953,0.0003275893,0.0008526934,0.0005711028,0.001018622,0.001348124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003686819,"about_ca_system_score_gemma":0.0004718677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000189518,"about_ca_topic_score_gemma":0.0005757437,"domain_scores_codex":[0.9994286,0.0001300582,0.00004621814,0.00009565413,0.0002510608,0.00004842064],"domain_scores_gemma":[0.9996915,0.0000740583,0.00009081543,0.00003441592,0.00007131694,0.00003802036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004199319,0.00004929792,0.0001438834,0.0004292457,0.00001006701,0.0001259023,0.00003395035,0.0007997041,0.9828377,0.002686888,0.0004366336,0.01240475],"study_design_scores_gemma":[0.000007024919,0.0001066504,0.0001587858,0.0000305075,0.000006833081,0.0001844757,0.00001618017,0.001053384,0.9847229,0.000474389,0.01322637,0.00001248241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3995699,0.04064607,0.5333594,0.001161007,0.000881932,0.0007666247,0.002218655,0.001572954,0.01982342],"genre_scores_gemma":[0.6264976,0.02479458,0.3369845,0.0004577785,0.0001904024,0.0005401624,0.002041447,0.0002994961,0.008193999],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001142596,"threshold_uncertainty_score":0.003822327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005515295168901036,"score_gpt":0.2507587176994125,"score_spread":0.2452434225305115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}