{"id":"W4386024071","doi":"10.1097/01.hs9.0000967904.29417.23","title":"S248: SIERRA TRIAL RESULTS WITH A TARGETED RADIOTHERAPY, IOMAB-B, A MYELOABLATIVE CONDITIONING WITH REDUCED INTENSITY TOLERABILITY YIELDS HIGH CR, LONG TERM SURVIVAL IN HSCT INELIGIBLE ACTIVE R/R AML","year":2023,"lang":"en","type":"article","venue":"HemaSphere","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ottawa Hospital","funders":"","keywords":"Medicine; Tolerability; Internal medicine; Fludarabine; Clinical endpoint; Hematopoietic stem cell transplantation; Population; Oncology; Transplantation; Total body irradiation; Randomized controlled trial; Gastroenterology; Surgery; Adverse effect; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009545156,0.0006538471,0.001056628,0.0002195436,0.0001692987,0.0009608705,0.0005391614,0.000837151,0.009356836],"category_scores_gemma":[0.0008810221,0.0002007345,0.001579147,0.0001853427,0.0004327887,0.0004315155,0.0002209118,0.00168854,0.001195833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003384481,"about_ca_system_score_gemma":0.0005634696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004170736,"about_ca_topic_score_gemma":0.001085575,"domain_scores_codex":[0.9997008,0.0001713068,0.00001929572,0.00004259125,0.00002391295,0.00004214638],"domain_scores_gemma":[0.9995366,0.0001087095,0.0001226972,0.00003660456,0.00002906837,0.0001662846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9461763,0.002685197,0.001804363,0.001200753,0.001083443,0.0001406296,0.00004630958,0.0005750383,0.01547697,0.0003861753,0.004991952,0.02543278],"study_design_scores_gemma":[0.8582559,0.1223086,0.008977583,0.0001494304,0.001766082,0.0003176493,0.00002641095,0.0005804904,0.002193268,0.000281706,0.005115758,0.00002701868],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770885,0.007380227,0.0005177924,0.001404895,0.0004435816,0.002046391,0.00438388,0.000254961,0.006479916],"genre_scores_gemma":[0.9851785,0.001874717,0.000836049,0.001190017,0.0004363724,0.001292303,0.00444006,0.00003924667,0.004712554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009356836,"threshold_uncertainty_score":0.03130168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03122284311210522,"score_gpt":0.3114139022138427,"score_spread":0.2801910591017375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}